[BIC-announce] Neuro Event: December 14, 4 pm - Special Seminar: "Mapping Drivers of Pathological Cognitive Aging using PET and MRI"

[Julien Doyon, Dr.]

Sent on behalf of Julien Doyon


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Monday, December 14, 2020
4:00 - 5:00PM EST
Zoom (Registration Required)<https://www.eventbrite.ca/e/special-seminar-mapping-drivers-of-pathological-cognitive-aging-using-pet-tickets-131912266139>
Speaker: Udunna Anazodo, PhD
PET/MRI Physicist and Principal Investigator, Lawson Health Research Institute, London, Ontario

Talk abstract
Premature or pathological cognitive aging is a leading cause of disability in older adults, often diagnosed at late and intractable stages of brain disorders (Alzheimer’s disease and other dementias). It is not clear why some older adults have symptoms suggestive of pathological cognitive aging and others don’t. Decades of research in cognitive aging point to a myriad of factors (biological, environmental -physical, psychosocial, and cultural- etc.) and precipitating events (injury including ischemic infarcts) that paint a picture of the complex processes and pathways associated with the initiation and development of pathological cognitive aging. Recent evidence suggest that these factors and events ubiquitously activate a triad of complex biological pathways that act separately or together to exert numerous biological effects that could culminate in accelerated and progressive cognitive decline. Vascular dysfunction - the breakdown in vessel wall structure and function -, oxidative stress, and inflammation are ubiquitous pathways that are activated systemically in almost all tissues in response to stress, trauma, infection, or injury, and more importantly are independently linked to the pathogenesis of Alzheimer’s disease and other dementias.

This talk will highlight emerging PET and MRI tools developed by my group to map the sequential and/or synergistic interactions of these key drivers of pathological cognitive aging in brains of live humans and animal models. And introduce ischemic heart disease post-myocardial infract as a novel disease model for mapping associations of these common drivers of tissue degeneration with known and emerging risk factors for accelerated cognitive decline – a new approach to understanding the initiation and development of pathological cognitive aging.

To register: Eventbrite<https://www.eventbrite.ca/e/special-seminar-mapping-drivers-of-pathological-cognitive-aging-using-pet-tickets-131912266139>

Host: Julien Doyon, Director, McConnell Brain Imaging Centre, The Neuro

Contact :  Sasha Kelly<mailto:sasha.kelly at mcgill.ca>

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Julien Doyon, Ph.D., FRSC, FCAHS
Directeur, Centre d’imagerie cérébrale McConnell
Director, McConnell Brain Imaging Center
Professeur, Département de neurologie et neurochirurgie
Professor, Department of Neurology and neurosurgery
McGill University

The Neuro #OpenScience
3801 University Street, Montréal, Quebec H3A 2B4
Bureau/Office: 514-398-5953; Cell.: 514-979-3488
julien.doyon at mcgill.ca<mailto:julien.doyon at mcgill.ca>
theneuro.ca<http://www.mcgill.ca/neuro/>; The BIC<https://www.mcgill.ca/bic/>: Web Page<https://www.mcgill.ca/neuro/julien-doyon-phd>


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