[BIC-announce] Fwd: Seminar tomorrow at 13:00 in BME 321: Magnetics-Based Toolbox for Lab-on-a-Chip technologies... By Dr. Nikola Pelas

[Bruce Pike]

Begin forwarded message:

> From: "David Juncker, Prof." <david.juncker at MCGILL.CA>
> Date: November 20, 2007 2:50:35 PM EST (CA)
> To: 217L-SEMINAR_NOTICE at LISTS.MCGILL.CA
> Subject: Seminar tomorrow at 13:00 in BME 321: Magnetics-Based  
> Toolbox for Lab-on-a-Chip technologies... By Dr. Nikola Pelas
> Reply-To: "David Juncker, Prof." <david.juncker at MCGILL.CA>
>
> Hi,
>
>
> Dr. Pekas is a new postdoc in my group who will present his thesis  
> and post-thesis work. Please don’t hesitate to forward to other  
> persons that may be interested.
>
> Everyone is welcome
>
> Best
>
> David
>
> Magnetics-Based Toolbox for Lab-on-a-Chip technologies: Integrated  
> Detection of Magnetic Particles and Droplets in Microfluidic Systems
>
>
> Nikola Pekas and Marc D. Porter
>
> Center for Combinatorial Sciences, The Biodesign Institute and the  
> Department of Chemistry and Biochemistry at Arizona State  
> University, Tempe, AZ 85287-6401
>
>
> Mark Tondra
>
> NVE Corp., Minneapolis, MN 55344 and Diagnostic Biosensors, LLC,  
> Minneapolis, MN 55414
>
> The study establishes a set of magnetics-based tools that have been  
> integrated with microfluidic systems. Details of design,  
> fabrication, and theoretical and experimental assessments will be  
> presented. The overall impact of the work begins to enable rapid and  
> efficient detection of magnetic entities such as particles, droplets  
> of ferrofluids, or biological targets. The detection has been  
> realized by deploying spin-valve Giant Magnetoresistance (GMR)  
> sensors – microfabricated structures originally developed for use as  
> readout elements in computer hard-drives. We successfully  
> transferred the GMR technology into the lab-on-a-chip arena.
>
> The presentation describes quantitative and rapid detection of  
> picoliter-sized droplets of magnetite nanoparticle suspensions in a  
> microfluidic system with an integrated array of spin-valve GMR  
> sensors. Magnetic droplets are formed on-chip, in a multiphase flow  
> scheme, by merging aqueous magnetic suspension with an immiscible  
> oil phase. The velocity, size, position, and frequency of targets  
> can readily be determined from the GMR response. Furthermore, the  
> observed signal provides information about the concentration and  
> magnetic properties of nanoparticles in individual picodroplets. The  
> limits of detection are determined and compared to numerical models,  
> thus defining some of the key design requirements for the creation  
> of a magnetics-based, microfluidic device capable of detecting and  
> enumerating discrete nanometric labels and magnetically labeled  
> biological analytes.
>
>
> -------------------------------------------------------------
>
> David Juncker, PhD
>
> Assistant Professor
>
> McGill University                       Tel:  + 1 (514) 398 7676
>
> Biomedical Engineering Dept.    Fax:  + 1 (514) 398 7461
>
> 3775, University St. rm #304    @:    david.juncker at mcgill.ca
>
> Montreal, QC, H3A 2B4           http://wikisites.mcgill.ca/djgroup
>
> Canada
>
> -
>
>
>
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