[BIC-announce] FW: Killiam Lecture - Tuesday, November 8, 2005
Jennifer Chew, Ms.
jennifer.chew at mcgill.ca
Mon Nov 7 15:47:45 EST 2005
PLEASE DISCARD IF THIS IS A DUPLICATE. JENNIFER
________________________________
From: MNISTAFF - Montreal Neurological Institute Staff
[mailto:MNISTAFF at LISTS.MCGILL.CA] On Behalf Of Enza Ferracane, Ms.
Sent: Monday, November 07, 2005 2:14 PM
To: MNISTAFF at LISTS.MCGILL.CA
Subject: FW: Killiam Lecture - Tuesday, November 8, 2005
Dear Colleagues,
It is my great pleasure to introduce you the next Killiam speaker,
Dr. David Eidelberg Director of the Neurosciences Research Center,
North Shore
Long Island Jewish Research Institute, Professor of Neurology and
Neurosurgery New York University School of Medicine and Director of
Movement Disorders program. Please Note the time of the talk will be at
1:00 on this Tuesday, Nov. 8th, not 4:00.
David has been using over the years functional brain imaging techniques
to
explore the mechanistic substrates of the movement disorders. With the
advent of regional covariance network analysis approach, he has been
able
to utilize metabolic data acquired with [18F] fluorodeoxyglucose (FDG)
PET
to identify characteristic patterns of functional neuropathology in
patients with movement disorders. For example, in Parkinson's disease
(PD)
he has demonstrated a disease-related metabolic brain network
correlating
with cell activity in the globus pallidus and with motor disability.
Importantly, the expression of this network seems to be modulated in a
predictable fashion by levodopa therapy and by pallidotomy. David has
also
applied this method to the study of deep brain stimulation (DBS) in
which
reversible network modulation can be demonstrated. Thus, metabolic brain
networks may serve as a useful imaging probe for objectively assessing
the
efficacy of therapeutic interventions for PD. Recently David has
extended
this network analytical approach from studies of glucose metabolism in
the
resting state to studies of brain activation during motor performance
using O-15 water. Using brain activation PET performed during
therapeutic
interventions for PD, he has been able to demonstrate how normal
brain-behavior relationships can be restored with successful therapy.
David is author and co-author of large number of publications and he has
received numerous honors and awards in the field of movement disorders.
He
is a great speaker and an outstanding neuroscientist who is looking
forward to this visit to our center.
I am looking forward to see you all at his presentation.
Antonio Strafella
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