[Preventad-mri] PREVENT-AD MRI call - TODAY, 10am

Thu Apr 23 12:41:20 EDT 2015

Hello,
Just to follow-up on the template questions we were discussing today.
My choice to normalize using the EPI template (vs. T1) was based on both
personal experience and the idea that normalize an image to another one
that is closer in image intensity and contrast distributions. I also ran
across this back when I was contemplating what course of action to take -
http://www.fil.ion.ucl.ac.uk/spm/course/slides05-usa/pdf/Lab_D_RegAlts.pdf

In my prior studies (across 3 different scanners) we faced lots of issues
with  normalization using the T1 images, regardless of where the data were
acquired.
So we switched to using EPI templates and it seemed to yield better
normalization.

I don't have a specific statistic/metric that we used to determine what was
'better' but instead looked a the individual subject GLMs and
Group level PLS to see if the t-statistics or spatial extents were
impacted.

I'd love to learn a more objective way to decide what the 'best'
normalization is since my lab is currently re-analyzing our data (from a
different study)
using multiple parallel normalization routines to try to find what works
best when you have sig. subject motion
(But again we are defining best as 'yields more sig results in
theoretically relevant ROIs'')
We are also exploring study-specific EPI templates since
Hsu et al. 2007 suggest that was optimal for their data.

I'd be happy to present what we find based on our various normalization
approaches in Fall 2015 to the group.
Cheers,
Natasha

On 23 April 2015 at 09:45, Cecile Madjar <cecile.madjar at gmail.com> wrote:

> Oops... Classic. I forgot the attachment. Here it is!
>
> Sorry for the multiple emails. Talk to you soon!
>
> Cécile
>
> On Thu, Apr 23, 2015 at 9:20 AM, Cecile Madjar <cecile.madjar at gmail.com>
> wrote:
>
>> Dear colleagues,
>>
>> You will find attached the meeting agenda for today's MRI call at 10am.
>> Information to join the call are below.
>>
>> Best wishes,
>>
>> Cécile
>>
>>>
>>> 1.  Please join my meeting, Apr 23, 2015 at 10:00 AM EDT.
>>> https://global.gotomeeting.com/join/545602461
>>>
>>> 2.  Use your microphone and speakers (VoIP) - a headset is recommended.
>>> Or, call in using your telephone.
>>>
>>> Dial  1 (647) 497-9372
>>> Access Code: 545-602-461
>>> Audio PIN: Shown after joining the meeting
>>>
>>> Meeting ID: 545-602-461
>>>
>>> GoToMeeting®
>>> Online Meetings Made Easy®
>>>
>>> Not at your computer? Click the link to join this meeting from your
>>> iPhone®, iPad®, Android® or Windows Phone® device via the GoToMeeting app.
>>>
>>> On Tue, Apr 14, 2015 at 9:19 AM, Cecile Madjar <cecile.madjar at gmail.com>
>>> wrote:
>>>
>>>> Dear colleagues,
>>>>
>>>> A friendly reminder to fill in the Doodle
>>>> <http://doodle.com/v299m2ieie2the7i> in order to schedule the MRI call.
>>>>
>>>> Thank you!
>>>>
>>>> Cécile
>>>>
>>>> On Fri, Apr 10, 2015 at 3:52 PM, Cecile Madjar <cecile.madjar at gmail.com
>>>> > wrote:
>>>>
>>>>> Dear colleagues,
>>>>>
>>>>> As discussed during our last MRI call, the time to schedule a call to
>>>>> discuss more specifically harmonization of analyses (choice of template,
>>>>> segmentation, smoothing...) has come.
>>>>>
>>>>> Please fill in the following Doodle
>>>>> <http://doodle.com/v299m2ieie2the7i> in order to schedule that call.
>>>>>
>>>>> Thank you for your collaboration.
>>>>> Best,
>>>>>
>>>>> Cécile
>>>>>
>>>>> --
>>>>> *Cécile Madjar*
>>>>> cecile.madjar at gmail.com
>>>>> Prevent Alzheimer Study: www.prevenir-alzheimer.ca
>>>>>
>>>>> StoP-AD Center
>>>>> Douglas Mental Health Institute
>>>>> Perry Pavillon
>>>>> 6875, boul. LaSalle
>>>>> Montréal, Qc, H4H 1R3
>>>>>
>>>>
>>>>
>>>>
>>>> --
>>>> *Cécile Madjar*
>>>> cecile.madjar at douglas.mcgill.ca <cecile.madjar at gmail.com>
>>>> Prevent Alzheimer Study: www.prevenir-alzheimer.ca
>>>>
>>>> StoP-AD Center
>>>> Douglas Mental Health Institute
>>>> Perry Pavillon
>>>> 6875, boul. LaSalle
>>>> Montréal, Qc, H4H 1R3
>>>>
>>>
>>>
>>>
>>> --
>>> *Cécile Madjar*
>>> cecile.madjar at douglas.mcgill.ca <cecile.madjar at gmail.com>
>>> Prevent Alzheimer Study: www.prevenir-alzheimer.ca
>>>
>>> StoP-AD Center
>>> Douglas Mental Health Institute
>>> Perry Pavillon
>>> 6875, boul. LaSalle
>>> Montréal, Qc, H4H 1R3
>>>
>>
>>
>>
>> --
>> *Cécile Madjar*
>> cecile.madjar at douglas.mcgill.ca <cecile.madjar at gmail.com>
>> Prevent Alzheimer Study: www.prevenir-alzheimer.ca
>>
>> StoP-AD Center
>> Douglas Mental Health Institute
>> Perry Pavillon
>> 6875, boul. LaSalle
>> Montréal, Qc, H4H 1R3
>>
>
>
>
> --
> *Cécile Madjar*
> cecile.madjar at douglas.mcgill.ca <cecile.madjar at gmail.com>
> Prevent Alzheimer Study: www.prevenir-alzheimer.ca
>
> StoP-AD Center
> Douglas Mental Health Institute
> Perry Pavillon
> 6875, boul. LaSalle
> Montréal, Qc, H4H 1R3
>
> _______________________________________________
> Preventad-mri mailing list
> Preventad-mri at bic.mni.mcgill.ca
> http://www.bic.mni.mcgill.ca/mailman/listinfo/preventad-mri
>
>

-- 
*Maria Natasha Rajah, Ph.D.*

*Director, Douglas Brain Imaging Centre, Douglas Institute Associate
Professor, Dept of Psychiatry, McGill UniversityAssociate Member, Dept. of
Psychology, McGill University*FRQ-S, Research Scholar - Junior 2

*#2114, CIC Pavilion, Douglas Institute6875 LaSalle Blvd Verdun, QC, H4H
1R3PHONE: 514-761-6131 p.2836; FAX:
514-888-4487http://www.douglas.qc.ca/researcher/maria-natasha-rajah
<http://www.douglas.qc.ca/researcher/maria-natasha-rajah>*
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