[MINC-users] Intracranial Volume?

[EJ Nikelski]

Hi All,

   I'm currently doing some cortical thickness regressions, and would
like to include a measure of intracranial volume as a covariate.  Now,
I know that I can get a measure of brain volume using either the Civet
(native) brain mask, or by summing the tissue classification
components (CSF,GM,WM), however, brain volume does not include the
volume of CSF located between the cortical surface and the inner
aspect of the skull.  For a normal, young population, these measures
may be effectively the same, but for elderly and demented, they are
not.  Any ideas?

Cheers,

-Jim


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Jim Nikelski, Ph.D.
Postdoctoral Research Fellow
Bloomfield Centre for Research in Aging
Lady Davis Institute for Medical Research
Sir Mortimer B. Davis - Jewish General Hospital
McGill University