[BIC-announce] Fwd: Reminder: Seminar Series in Quantitative Life Sciences and Medicine - Martin Lindquist - November 24, 12:30-1:30pm (Please Note the Time)

[JB Poline]

Hi,
For those interested, I invited Martin Linquist to talk tomorrow at the QLS
seminar, see below
Cheers
JB

---------- Forwarded message ---------
From: QLS Coordinator <coordinator.qls at mcgill.ca>
Date: Mon, Nov 23, 2020 at 10:39 AM
Subject: Reminder: Seminar Series in Quantitative Life Sciences and
Medicine - Martin Lindquist - November 24, 12:30-1:30pm (Please Note the
Time)
To:


*Principal Directions of Mediation*

Martin Lindquist, Johns Hopkins University
Tuesday November 24, 12:30-1:30pm *(Please Note the Time)*
Zoom Link: https://mcgill.zoom.us/j/91589192037

Abstract: Mediation analysis is an important tool in the behavioral
sciences for investigating the role of intermediate variables that lie in
the path between a randomized treatment/exposure and an outcome variable.
The influence of the intermediate variable on the outcome is often explored
using structural equation models (SEMs), with model coefficients
interpreted as possible effects. While there has been significant research
on the topic in recent years, little work has been done on mediation
analysis when the intermediate variable (mediator) is a high-dimensional
vector. In this work we introduce a novel method for mediation analysis in
this setting called the principal directions of mediation (PDMs). We
demonstrate the method using a functional magnetic resonance imaging (fMRI)
study of thermal pain where we are interested in determining which brain
locations mediate the relationship between the application of a thermal
stimulus and self-reported pain.

Alexander DeGuise | QLS Coordinator | Quantitative Life Sciences | McGill
University

Wilson Hall, room 226 | 3506 University Street | Montreal, Canada H3A 2A7

Tel: +1 514-398-4826 | coordinator.qls at mcgill.ca | www.mcgill.ca/qls

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