[BIC-announce] Seminar in Biomedical Engineering - Wednesday March 19th - 1h pm - Room 333

[Christophe Grova]

Dear all, 

We will have our next  Biomedical Engineering seminar today

Wednesday  ­ March 19th,  at 1 pm

Location: Room  333 Lyman Duff Building (Biomedical Engineering Dpt, 3775
University Street).

Speaker:  Ryan Tien Sing Young, Master student under the supervision of Dr
M. Tabrizian PhD, BME, McGill University

Since Ryan is a Master student registered to the course BMDE500 who is
giving this seminar as part of McGill conditions to obtain his M.Sc.,
special attendance from our department (staff and students) is really
expected, in order to give Ryan feedback on his research studies.

Title: 
"Increasing liposome drug encapsulation efficiency via passive ?fluidic
synthesis"


Abstract:
Since their discovery more than half a century ago, liposomes have been used
as vehicles for drug delivery, vessels for contrast agents in medical
imaging and even carriers of food flavours and nutrients in the food
industry. Among many other advantages, their biocompatibility and ability to
encapsulate hydrophobic, hydrophilic or amphiphilic bioactive compounds make
them ideal for this wide range of applications. However, liposome synthesis
is oftentimes a very time consuming process, and loading of desired
molecules can be very difficult. Here, we propose a simple continuous-flow,
passive microfluidic device which combines the synthesis and loading steps
into a single low-cost device. Combining the traditional method of direct
ethanol injection with microfluidic hydrodynamic focusing, also known as
flow focusing, our preliminary results demonstrate the ability to synthesize
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) micro- and nanoparticles
simply by varying the flow rates to the device. Not only can this design be
used as a low-volume test bed for new liposome formulations, but potentially
as a development platform for other types of micro-/nanoparticles as well.



A list of upcoming seminars can be found at :
http://www.mcgill.ca/bme/news/seminars

See you there 

 
Christophe Grova 

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Christophe Grova, PhD
Assistant Professor
Biomedical Engineering Dpt
Neurology and Neurosurgery Dpt
 
Multimodal Functional Imaging Lab (Multi FunkIm)
Montreal Neurological Institute
Centre de Recherches en Mathématiques
 
Biomedical Engineering Department - Room 304
McGill University
3775 University Street, Montreal, Quebec, Canada,
H3A 2B4 
email : christophe.grova at mcgill.ca <mailto:christophe.grova at mcgill.ca>
tel : (514) 398 2516
fax : (514) 398 7461
 
Web:
http://www.bic.mni.mcgill.ca/ResearchLabsMFIL/PeopleChristophe
http://www.bmed.mcgill.ca/
MultiFunkIm Lab:
http://www.bic.mni.mcgill.ca/ResearchLabsMFIL/HomePage
 
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