[BIC-announce] Seminar in Biomedical Engineering - Wednesday Sept 25th - 1 pm - Room 333

[Christophe Grova]

Dear all,

We will have our next Biomedical Engineering seminar this coming wednesday

Wednesday - September 25th,  at 1 pm

Location: Room  333 Lyman Duff Building (Biomedical Engineering Dpt, 3775
University Street).
 
Speaker: Dr Nikola Stikov PhD, postdoctoral fellow under the supervision of
Dr B Pike, McConnell Brain Imaging Center, McGill Univeristy

Title: In vivo magnetic resonance imaging of the myelin g-ratio

Abstract: The myelin g-ratio, defined as the ratio between the axon caliber
and
the total caliber of the axon plus its myelin sheath, has been
proposed as an important biomarker for studying normal brain
development, as well as brain pathology. Recent studies have suggested
that the sexual dimorphism in white matter development is due to a
higher g-ratio (thinner myelin) in adolescent boys. Variations in the
g-ratio have also been detected in the frontal white matter of
patients with schizophrenia. Finally, in vivo imaging of the myelin
thickness in multiple sclerosis can provide a real-time tool for
tracking myelination in lesions, fascilitating the development and
evaluation of new therapeutic agents that promote remyelination.  In
this lecture, a unique combination of quantitative magnetic resonance
imaging, histology, and numerical simulations will be presented,
resulting in a novel method for in vivo measurement of the myelin
g-ratio. The ramifications of this method will be discussed in the
context of applications and validation in animal models.


A list of upcoming seminars can be found at :
http://www.mcgill.ca/bme/news/seminars

See you there 

 
Christophe Grova 


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Christophe Grova, PhD
Assistant Professor
Biomedical Engineering Dpt
Neurology and Neurosurgery Dpt

Montreal Neurological Institute
Centre de Recherches Mathématiques

Biomedical Engineering Department - Room 304
McGill University
3775 University Street, Montreal, Quebec, Canada, H3A 2B4
email : christophe.grova at mcgill.ca
tel : (514) 398 2516
fax : (514) 398 7461
 
web:
http://www.mni.mcgill.ca/research/gotman/members/christophe.html
http://www.bmed.mcgill.ca/
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