[BIC-announce] Special Additional Seminar in Biomedical Engineering - FRIDAY February 15th - 1 pm - Room 333

[Christophe Grova]

Dear all,


A reminder that we will  have a special seminar  today at 13h,  from Dr.Kinsella who is candidate for associate membership in our department.

Friday - February 15th,  at 1 pm

Location: Room  333 Lyman Duff Building (Biomedical Engineering Dpt, 3775  University Street).

Speaker: Dr Joseph "Matt" Kinsella PhD,   Department of Bioengineering, McGill University

Dr. Kinsella  is candidate for associate membership in Biomedical Engineering department, so attendance from our staff members and their students is highly encouraged.

Title :  Aiding Tumor Visualization with Nanomaterials

Abstract:

Cancer diagnoses, and increasingly treatment, are progressively being aided by the development of new medical and molecular imaging technologies.  Central to the utility of these procedures has been the concurrent development of contrast agents that enable clinicians to clearly delineate tumor peripheries, determine pathologies, and develop personalized intervention strategies.  Nanotechnology has provided innovative materials that have been proven to provide elevated contrast in a number of different imaging modalities.  Specifically, tumor tissue-specific nanoparticles have shown great potential as contrast agents for the direct in vivo detection of a number of cancers.

This seminar w<https://exchange.mcgill.ca/owa/?ae=PreFormAction&a=Forward&t=IPM.Note&id=RgAAAAB30pnPgDtWS7a7w4Xl4JjIBwD%2bSveATrNNT7f5235%2buCBUAAADj26VAACeFkfto%2bu0Sq2hYs7ExCIuAAABmtfZAAAJ&pspid=_1360935495128_341725436#>ill focus on two examples of nanoscale contrast agents.  The first of these is a composite material consisting of Fe3O4 nanoparticles embedded in a 200 nm diameter porous Si nanoparticle “superstructure.” The composite exploits the dipolar coupling of superparamagnetic nanoparticles trapped within a secondary inorganic matrix, and has been shown to enhance the transverse relaxivity contrast in a 3 T MRI more than 1.6 fold when compared to similar, unencapsulated Fe3O4 nanoparticles.  The second half of the talk will describe the enhanced visualization of breast cancer in X-ray Computed Tomography that was achieved by using Bi2S3 nanoparticles of 10 nm diameter modified to display a tumor targeting peptide (LyP-1, CGNKRTRGC). In these studies the accumulation of the nanoparticle contrast agent within the tumor was increased by 260% compared to nanoparticles that did not contain the homing peptide.


A list of upcoming seminars can be found at : http://www.mcgill.ca/bme/news/seminars

See you there


Christophe Grova


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Christophe Grova, PhD
Assistant Professor
Biomedical Engineering Dpt
Neurology and Neurosurgery Dpt

Montreal Neurological Institute
Centre de Recherches Mathématiques

Biomedical Engineering Department - Room 304
McGill University
3775 University Street, Montreal, Quebec, Canada, H3A 2B4
email : christophe.grova at mcgill.ca
tel : (514) 398 2516
fax : (514) 398 7461

web:
http://www.mni.mcgill.ca/research/gotman/members/christophe.html
http://www.bmed.mcgill.ca/
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