[BIC-announce] Upcoming CREATE-MIA Events: September 13, 2013

Krys Dudek kdudek at cim.mcgill.ca
Tue Aug 27 09:51:19 EDT 2013


Hi all,

The first CREATE-MIA events of the fall term will take place on Friday, September 13 in MC103.

10:00am - 1:00pm  IP Workshop (by registration ONLY:  http://aggie.cim.mcgill.ca.:8080/create-mia/forms/create-mia-ip-whats-in-it-for-me)
This will be led by Mr. Hugh Mansfield, a patent lawyer and senior partner at Goudreau Gage Dubuc in Montreal and member of both the Quebec Bar and the Quebec Order of Engineers.  The workshop will consist of two parts. The first, a presentation entitled "IP: What's in it for me?"  will aim to give participants a better understanding of what IP and how to make the most of their inventions and creations by protecting the IP built into them.  The second part will be a case study in which various issues inherent in software ownership will be explored.  I will be forwarding you some material that you will be asked to prepare before the workshop as the workshop draws nearer.  The workshop is being offered through the IP Bank of Speakers, a collaborative effort of the Canadian Property Office (CIPO) and the Intellectual Property Institute of Canada (IPIC).

2:30pm - 3:30pm  Seminar: "Building Atlases of Heart Wall Fibers" by Prof. Kaleem Siddiqi (School of Computer Science and CIM, McGill)
Abstract: Studies of cardiac fiber variability within a species tend to focus on first-order measures such as local fiber orientation. Recent work has shown that myofibers bundle locally into a particular type of minimal surface, the generalized helicoid model (GHM), which is described by three biologically meaningful curvature parameters. In order to allow comparisons between species, a typical strategy is to divide the parameters of the generalized helicoid by heart wall diameter. This normalization does not compensate for variability in myocardial shape between subjects and makes the interpretation of results difficult. We propose to use several myocardial atlases, obtained using diffeomorphic groupwise Log-demons, to register all hearts to a common reference shape to perform the normalization. In this common space, the GHM is estimated for all hearts and compared using an improved fitting method. Our results demonstrate improved consistency between GHM curvatures within a species and support a direct relation between myocardial shape and fiber curvature in the heart.

3:30pm- 4:30pm Seminar: "Imaging and Operative Techniques for Glioma Surgery" by Dr. Kevin Petrecca  (Department of Neurology and Neurosurgery, McGill)
Abstract:
Malignant gliomas are the most common adult primary brain cancers and are amongst the most devastating of human malignancies. These cancers are characterized by high proliferation and invasion into normal brain. The goal of surgery is to remove the entirety of the tumor as strong emerging evidence suggests that completeness of resection improves cancer control and lengthens survival.

Studies examining the location of malignant glioma recurrence following surgery and adjuvant radiotherapy and chemotherapy have found that most cancers recur within a 1 cm border along the surgical resection cavity, even in cases in which no residual gadolinium-enhancing tumor was evident on immediate post-operative MRI. This suggests that gadolinium-enhanced MRI does not sufficiently reveal the entire tumor resulting in residual tumor post-operatively. Other common MRI sequences, including FLAIR and T2, do not adequately distinguish non-gadolinium enhancing cancer cells from peritumoral edema. The inability to accurately visualize the whole tumor, including invasive cells, on imaging decreases the likelihood of complete resection.
Since malignant gliomas are highly invasive tumors, the margin between tumor and normal brain is typically not obvious. Reluctant to cause an irreversible neurological deficit, surgeons will error on the side of caution. The downside is that malignant cancer cells will remain. Since adjuvant radiation and chemotherapies are only modestly effective, these cancer cells that remain along the border of the original tumor mass will recur.  Intraoperative tools designed to help surgeons distinguish cancer cells from normal brain include ultrasound and fluorescence guided surgical resection.  Comparative studies using these tools have shown higher rates of complete resection compared to standard operating techniques.
In this session we will review current and emerging imaging technologies designed to better visualize the tumor on preoperative imaging. We also review developing surgical technologies to help surgeons distinguish cancer cells from normal brain intraoperatively. The development of these technologies will lead to an increased rate of complete resection and thus improved cancer control.




Full details can be found on the CREATE-MIA website (http://aggie.cim.mcgill.ca.:8080/create-mia). All three sessions will take place in MC103 (McConnell Engineering  Building, 3480 University Street).  A map showing the location of the building can be found at http://aggie.cim.mcgill.ca.:8080/create-mia/about/contact-us

IMPORTANT:  The IP Workshop requires registration.  This can be done online at http://aggie.cim.mcgill.ca.:8080/create-mia/forms/create-mia-ip-whats-in-it-for-me.   The two afternoon seminars are open to all.




Cheers,

Krys

_________________________________________________________
Krys (Christine) Dudek
Program Administrator, NSERC CREATE Program for Medical Image Analysis
Centre for Intelligent Machines
3480 University Street
McConnell Engineering Building, Room 410
Montreal, Quebec, Canada
H3A 2A7

kdudek at cim.mcgill.ca
514.398.6319

www.cim.mcgill.ca/create-mia

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