[BIC-announce] Seminar in Biomedical Engineering - WednesdayOctober 10th - 1 pm- Room 333

[Christophe Grova]

Dear all, 

Our  next Biomedical Engineering Dpt seminar is today
Wednesday - October 10th,  at 1 pm 


Location: Room  333 Lyman Duff Building  - Biomedical Engineering Dpt, 
3775 University Street.


Speaker: Dr. Elizabeth Jones PhD, Mechanical Engineering, McGill University, Montreal, Canada


Title : Shear stress and Vascular Remodelling During Development

Abstract:
Every tissue in the body requires blood flow to bring nutrients to the tissue. For this reason, there is significant therapeutic advantage to controlling when and where new blood vessels develop. It is known that many genes regulated by shear stress are also important for developmental blood vessel formation. We have thus begun investigating the interaction of genetic and mechanical signals during vascular development. We previously showed that shear stress is necessary for proper vascular development and vascular remodelling. We use various means to alter shear stress during development in order to investigate the role of hemodynamics during embryonic development. Angiogenesis is the formation of new blood vessels and our current results show that shear stress is inhibitory to angiogenesis. Furthermore, we investigate the mechanism of shear-induced inhibition and find it to be dependent on BMP signaling. We have also been studying when the cardiovascular system is first sensitive to shear stress by investigating the development of mechanotransduction mechanisms in the embryo. 

 

A list of upcoming seminars can be found at : http://www.mcgill.ca/bme/news/seminars


See you there



Christophe Grova 



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Christophe Grova, PhD 
Assistant Professor
Biomedical Engineering Dpt 
Neurology and Neurosurgery Dpt 

Montreal Neurological Institute
Centre de Recherches en Mathématiques

Biomedical Engineering Department - Room 304
McGill University
3775 University Street, Montreal, Quebec, Canada, H3A 2B4
email : christophe.grova at mcgill.ca
tel : (514) 398 2516
fax : (514) 398 7461
 
web: 
http://www.mni.mcgill.ca/research/gotman/members/christophe.html
http://www.bmed.mcgill.ca/
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