[BIC-announce] Seminar in Biomedical Engineering - Wednesday October 3rd - 1 pm- Room 333

[Christophe Grova]

Dear all, 

Our  next Biomedical Engineering Dpt seminar is TODAY

Wednesday - October 3rd,  at 1 pm 


Location: Room  333 Lyman Duff Building (Biomedical Engineering Dpt, 3775 
University Street).


Speaker: Dr. Pierre Bellec  PhD, Assistant Professor, Centre de Recherches de l'Institut Universitaire de Gériatrie de Montréal, Université de Montréal, 
Département d'informatique et de recherche opérationnelle (DIRO) 

Title : Multiscale and multilevel bootstrap analysis of stable clusters in fMRI

Abstract:
Functional MRI gives an indirect measure of brain activity with good spatial and temporal resolution. Clustering techniques can be used to summarize such large datasets into brain networks, i.e. groups of brain regions with similar temporal activity. The cluster analysis of an fMRI database raises (at least) two challenges. First, it has long been hypothesized that the brain follows a modular organization where large systems (such as visual, motor, etc) can be further decomposed into subnetworks with an increasing level of functional specialization. The cluster analysis thus needs to be performed at multiple scales (i.e. number of networks). Second, even after a perfect anatomical coregistration, the functional cerebral architecture will vary from subjects to subjects. It is thus necessary to find a multi-level clustering model that is flexible enough to capture individual features while finding a consistent solution across subjects (so that individual cluster maps can be compared at the group level). In this talk I will discuss a technique called bootstrap analysis of stable clusters (BASC) [1,2], which can be used to perform multilevel and multiscale analysis of resting-state fMRI. I will present new results showing how this technique applies in the context of task-based fMRI. 


[1] P. Bellec; V. Perlbarg; S. Jbabdi; M. Pélégrini-Issac; J.L. Anton; H. Benali, Identification of large-scale networks in the brain using fMRI. Neuroimage, 2006, 29: 1231-1243. 
[2] P. Bellec; P. Rosa-Neto; O.C. Lyttelton; H. Benalib; A.C. Evans, Multi-level bootstrap analysis of stable clusters in resting-State fMRI. Neuroimage 51 (2010), pp. 1126-1139


A list of upcoming seminars can be found at : http://www.mcgill.ca/bme/news/seminars


See you there



Christophe Grova 



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Christophe Grova, PhD 
Assistant Professor
Biomedical Engineering Dpt 
Neurology and Neurosurgery Dpt 

Montreal Neurological Institute
Centre de Recherches en Mathématiques

Biomedical Engineering Department - Room 304
McGill University
3775 University Street, Montreal, Quebec, Canada, H3A 2B4
email : christophe.grova at mcgill.ca
tel : (514) 398 2516
fax : (514) 398 7461
 
web: 
http://www.mni.mcgill.ca/research/gotman/members/christophe.html
http://www.bmed.mcgill.ca/
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