[BIC-announce] Seminar in Biomedical Engineering - Wednesday April 11th at 13h

[Christophe Grova]

Dear all,

Our next Biomedical Engineering Dpt seminar is this coming Wednesday 

Wednesday - April 11th,  at 13h

Location: Room  333 Lyman Duff Building (Biomedical Engineering Dpt, 3775 University Street).

Speaker: Dr. A. Adamantidis Ph.D. Researcher, Douglas Hospital Research Centre

Assistant Professor, Department of Psychiatry, McGill University

Title: Optogenetic probing of sleep-wake circuits in the brain

Abstract:
The functions of sleep remains a mystery and the neural substrates involved are the subject of intense study. Successive sleep and wakefulness cycles rely on an appropriate balance between sleep-promoting nuclei of the brain, including inhibitory cells of the ventro-lateral preoptic area and anterior hypothalamus and, arousal-promoting nuclei from the brainstem and the posterior hypothalamus. Hence, the hypothalamus contains cell types able to regulate the occurrence and maintenance of sleep and wake events. Indeed, two distinct neuron populations restricted to the hypothalamus have been recently identified as critical modulators of the sleep-wake cycle: the Hypocretins- (Hcrt1,2, also known as OrexinsA,B)- and Melanin-Concentrating Hormone (MCH)-expressing neurons. We have previously shown that the Hcrt system is involved in promoting wakefulness. However, the role of MCH neurons on the sleep-wake cycle remains unclear. This presentation will summarize the application of in vitro and in vivo optogenetics to characterize the mechanisms implicated in the control of sleep state onset and maintenance.

A list of upcoming seminars can be found at : http://www.mcgill.ca/bme/news/seminars

See you there

Christophe Grova

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Christophe Grova, PhD
Assistant Professor
Biomedical Engineering Dpt
Neurology and Neurosurgery Dpt
Montreal Neurological Institute
Centre de Recherches en Mathématiques
Biomedical Engineering Department - Room 304
McGill University
3775 University Street, Montreal, Quebec, Canada, H3A 2B4
email : christophe.grova at mcgill.ca<mailto:christophe.grova at mcgill.ca>
tel : (514) 398 2516
fax : (514) 398 7461

web:
http://www.mni.mcgill.ca/research/gotman/members/christophe.html
http://www.bmed.mcgill.ca/
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