[BIC-announce] FW: Mark Lewandoski lecture - Thursday May 15th - The role of FGF signaling in outgrowth and patterning of embryonic structures

[Jennifer Chew, Ms.]

PLEASE DISCARD IF THIS IS A DUPLICATE.  THANK YOU.  JENNIFER 
 
This Thursday at 3pm, Mark Lewandoski from the NCI in Maryland will be giving a special lecture at the MNI de Grandpré room of the BTRC. Mark is an old friend from UCSF. As a post-doc with Gail Martin, he played a key role in the development of cre and flp mediated recombination strategies to generate conditional knockouts in mice. A substantial amount of his work has focused on roles for FGF signaling regulating patterning, both in the CNS and in other organ systems; however, his work goes well beyond FGFs. Mark has published many high profile papers, but to provide just one example, with Gail Martin, he described a method for selectively deleting an entire chromosome at a specific time during mouse development. 

Lewandoski M, Martin GR. Cre-mediated chromosome loss in mice. Nat Genet. 1997 Oct;17(2):223-5.

Mark is a very creative scientist and an equally engaging speaking. Let me know if you or someone in your lab would like to meet with Mark during his visit. 

Best

Tim Kennedy (398-7136)   

Special Lecture 

3 pm to 4 pm May 15 

Brain Tumour Research Centre - de Grandpré Communications Centre
 Title   "The role of FGF signaling in outgrowth and patterning of embryonic structures"

Mark Lewandoski, Ph.D.
Genetics of Vertebrate Development Section
National Cancer Institute
Frederick Cancer Research & Development Center
Frederick, Maryland, USA

Recent papers include the following: 

Aulehla A, Wiegraebe W, Baubet V, Wahl MB, Deng C, Taketo M, Lewandoski M, Pourquié O. A beta-catenin gradient links the clock and wavefront systems in mouse embryo segmentation. Nat Cell Biol. 2008 Feb;10(2):186-93. 

 Dunty WC Jr, Biris KK, Chalamalasetty RB, Taketo MM, Lewandoski M, Yamaguchi TP. Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation. Development. 2008 Jan;135(1):85-94. 

Wahl MB, Deng C, Lewandoski M, Pourquié O. FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis. Development. 2007 Nov;134(22):4033-41.

Jacques BE, Montcouquiol ME, Layman EM, Lewandoski M, Kelley MW. Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea. Development. 2007 Aug;134(16):3021-9. 

Pajni-Underwood S, Wilson CP, Elder C, Mishina Y, Lewandoski M. BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling. Development. 2007 Jun;134(12):2359-68.

Waters ST, Lewandoski M. A threshold requirement for Gbx2 levels in hindbrain development. Development. 2006 May;133(10):1991-2000.

Perantoni AO, Timofeeva O, Naillat F, Richman C, Pajni-Underwood S, Wilson C, Vainio S, Dove LF, Lewandoski M. Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development. Development. 2005 Sep;132(17):3859-71.