[BIC-announce] FW: Killam Lecture - TODAY - In Vivo Imaging and Genetic Analysis of Vertebrate glia Development

[Jennifer Chew, Ms.]

PLEASE DISCARD IF THIS IS A DUPLICATE.  THANK YOU.  JENNIFER 
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KILLAM LECTURE - TODAY

Speaker:  Bruce H. Appel, PhD, Department of Biological Science,
Vanderbilt University, Nashville, TN

Title:  In Vivo Imaging and Genetic Analysis of Vertebrate Glia
Development

Time: 4:00 pm

Place: de Grandpre Communications Centre

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The April 22 Killam lecture will be given by Bruce H. Appel, PhD, Dept
of Biological Sciences, Vanderbilt University, Nashville. The Appel lab
uses in vivo live cell imaging to investigate molecular genetic
mechanisms that regulate cell fate specification, cell migration, and
differentiation in the developing zebrafish nervous system. Recent
papers have provided exciting insight into mechanisms of oligodendrocyte
migration and differentiation, and evidence for a new class of CNS
derived glial cells.  

 

The title of his talk is, 

In vivo imaging and genetic analysis of vertebrate glia development

 

Please join us for a fascinating seminar. 

 

Tim Kennedy

 

Recent Publications from the Appel Lab

 

Kucenas S, Takada N, Park HC, Woodruff E, Broadie K, Appel B.
CNS-derived glia ensheath peripheral nerves and mediate motor root
development. Nat Neurosci. 2008 Feb;11(2):143-51.

 

Sarmah B, Winfrey VP, Olson GE, Appel B, Wente SR. Notch signaling
regulates neural precursor allocation and binary neuronal fate decisions
in zebrafish. Development. 2007 May;134(10):1911-20. 

 

Shin J, Poling J, Park HC, Appel B. An olig2 reporter gene marks
oligodendrocyte precursors in the postembryonic spinal cord of
zebrafish. Dev Dyn. 2007 Dec;236(12):3402-7. 

 

Shin J, Poling J, Park HC, Appel B. Notch signaling regulates neural
precursor allocation and binary neuronal fate decisions in zebrafish.
Development. 2007 May;134(10):1911-20. 

 

Kirby BB, Takada N, Latimer AJ, Shin J, Carney TJ, Kelsh RN, Appel B. In
vivo time-lapse imaging shows dynamic oligodendrocyte progenitor
behavior during zebrafish development.

Nat Neurosci. 2006 Dec;9(12):1506-11. 

 

Park HC, Boyce J, Shin J, Appel B. Oligodendrocyte specification in
zebrafish requires notch-regulated cyclin-dependent kinase inhibitor
function. J Neurosci. 2005 Jul 20;25(29):6836-44. 

 

Park HC, Appel B. Delta-Notch signaling regulates oligodendrocyte
specification.

Development. 2003 Aug;130(16):3747-55.

 

Park HC, Shin J, Appel B. Spatial and temporal regulation of ventral
spinal cord precursor specification by Hedgehog signaling. Development.
2004 Dec;131(23):5959-69. 

 

Park HC, Mehta A, Richardson JS, Appel B. olig2 is required for
zebrafish primary motor neuron and oligodendrocyte development. Dev
Biol. 2002 Aug 15;248(2):356-68.