[BIC-announce] FW: SPECIAL LECTURE - TODAY - Adult polyglucosan body disease: A rich source of information about glucose-glycogen metabolism of neurons

[Jennifer Chew, Ms.]

PLEASE DISCARD IF THIS IS A DUPLICATE.  THANK YOU.  JENNIFER
 

 

REMINDER


Dear Colleagues,

On Monday, April 21, 2008, from 11 am to 12-noon, there will be a
SPECIAL LECTURE entitled "Adult polyglucosan body disease: A rich source
of information about glucose-glycogen metabolism of neurons" in Grandpre
Centre Auditorium, MNI. The lecturer is Dr. Alexander Lossos, an
Associate Professor of Neurology at the Hadassah Hospital-Hebrew
University in Jerusalem, Israel. Dr. Lossos is presently a Visiting
Professor with the Neuromuscular Group at the MNI. He is an
internationally known physician scientist who is an authority in a rare
but highly instructive disease of the nervous system, called ADULT
POLYGLUCOSAN BODY DISEASE (APGBD). He has the largest series of patients
in the world and made seminal discoveries in APGBD including the
identification of the metabolic defect (glycogen branching enzyme [BE]
deficiency) and identified a common mutation in the BE gene. APGBD is a
relative rare disease but it is a very useful model for the
understanding of glycogen/glucose metabolism of neurons. Thus, even
basic neuroscientists would derive hitherto unknown knowledge about
carbohydrate-based energy metabolism of neurons and axonal transport.
Furthermore, there are intensive efforts for the development of
molecular therapies for APGBD which would permit a glance at the status
of gene therapy for the central nervous system. Dr. Lossos is an
excellent speaker and he will cover all these and additional aspects of
APGBD. Nobody (neither clinician nor basic neuroscientist) should miss
this golden opportunity for expanding one's knowledge in such important
areas. 

George Karpati