[BIC-announce] SEMINAR - Image-Guided Therapeutic Ultrasound: A Method for Non-Invasive, Deep Tissue Treatment, Wednesday, March 29

[Jennifer Chew, Ms.]

                     SEMINAR

 

 

Image-Guided Therapeutic Ultrasound: A Method for Non-Invasive, Deep
Tissue Treatment

 

Dr. Vesna Zderic

Department of Bioengineering, University of Washington

 

Wednesday, March 29, 2006 at 11:00 am 

Conference Room 603, McConnell Engineering Building 

 

Development of image-guided therapeutic ultrasound devices has
experienced significant progress in recent years for applications in
non-invasive treatment of tissues located deep inside the body.  High
Intensity Focused Ultrasound (HIFU) provides a method for delivery of a
large amount of energy to a mm-size focal spot to produce coagulation
necrosis, while sparing the intervening tissues from harmful exposure.
Successful HIFU application requires seamless integration and
synchronization with an imaging modality for therapy guidance and
monitoring.  Various imaging methods provide different capabilities; for
example ultrasound imaging is real time, portable, and affordable, while
MRI offers thermal measurement capabilities and excellent soft tissue
contrast.  Image-guided HIFU is currently being investigated for
non-invasive hemorrhage control and treatment of various tumors.  In
addition, ultrasound at medium-intensities has been successfully applied
in the treatment of stroke and other vascular diseases, targeted drug
and gene delivery, and wound healing.  In this talk, I will particularly
focus on my current and future work in the following areas: 

      1) Optimization of ultrasound-image guided HIFU therapy.  The
examples include: Application of ultrasound contrast agents for enhanced
HIFU-induced hemostasis and bleeding detection for trauma management
during Space missions (funded by NASA); Selective occlusion of blood
vessels (similar to angioembolization) using ultrasound-guided HIFU
phased arrays; Utilization of acoustic cavitation for real-time guidance
of tumor treatment, as well as a safety measure to prevent HIFU exposure
to post-focal regions; Development of portable, smart devices for
battlefield trauma, especially for treatment of peripheral vascular
injuries (funded by DARPA).    

      2) Application of medium-intensity ultrasound for enhancement of
drug delivery.  Optimization of ultrasound parameters for delivery of
hydrophilic compounds into the eye, and future plans for application of
image-guided therapeutic ultrasound for targeted drug delivery into
various organs will be discussed.

 

 

 

Deborah Davies

Administrative Assistant

Electrical & Computer Engineering

McGill University

Tel:  (514) 398-7111

Fax: (514) 398-4470

deborah.davies at mcgill.ca

 

 

 

Jennifer Chew

McConnell Brain Imaging Centre

MNI - WB317

3801 University Street

Montreal, Qc  H3A 2B4

Telephone:  514-398-8554

Fax:  514-398-2975

 

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