From cchappel at med.unc.edu Fri Mar 7 18:15:09 2025 From: cchappel at med.unc.edu (Chappell, Chad) Date: Fri, 7 Mar 2025 23:15:09 +0000 Subject: [Ace-recruitment] IBIS Network - Week In Review - 3/7/2025 In-Reply-To: <9E7B52DB-F791-4278-9388-E19680AC4857@med.unc.edu> References: <4CE497B8-8CF1-4B8D-BFF1-7434BAE3DEC0@med.unc.edu> <301BB957-BDFD-461A-8BEF-FC6BB90243B3@med.unc.edu> <4429ADBB-E418-4A1D-B9F6-D668A1BF208E@med.unc.edu> <6133D561-4809-4C76-BA60-A7ED0B8082B8@med.unc.edu> <44BE26D7-E8B2-4A4B-8FFB-8714AE18BECC@med.unc.edu> <171A7FF3-1C1C-4D10-9C52-FB829D373268@med.unc.edu> <55E64F6D-EA94-4088-9C4C-5A8866F27375@med.unc.edu> <110A51CD-F2E9-4DA8-8830-881B6DBBAD47@med.unc.edu> <96FA8F52-598D-4B8D-AA8D-877658827C77@med.unc.edu> <9E7B52DB-F791-4278-9388-E19680AC4857@med.unc.edu> Message-ID: <8802CB6A-86AD-452C-8156-33EC1A2C8B6C@med.unc.edu> IBIS Week In Review 3/7/2025 IBIS DS Renewal Submission The IBIS-DS Renewal has been submitted. Congratulations to Natasha, Heather and everyone who helped get this across the finish line! IBIS Internship 2025 Interns Selected A huge welcome to two fantastic interns for the IBIS Network this summer! Aldair Argueta-Vazquez will be working with Becca Grzadzinski and Jose Rodriguez-Romaguera at UNC and Miftahul Jannat will be working with Chimei Lee at UMN. IBIS Executive Committee Approvals Martin Styner - MICCAI Submission: "Predicting Cognitive Outcomes by Mapping White Matter Tracts to Surface White Matter Tracts to Surface? Here, we propose a new framework for convolutional deep learning on white matter tract data. Rather than directly analyzing the tracts as individual measures, we propagate the tract information to the cortex. This way we can combine both structural information (surface area, cortical thickness) and diffusion information (propagated tract data) via a graph-based convolutional network (GCN) on regional cortex data. We evaluate this on IBIS1-2 and EBDS (PI Gilmore) data, predicting 2y Mullen from 1y structure & diffusion data. Martin Styner - MICCAI Submission: "Phenotype Representation and Analysis via Discriminative Atypicality (PRADA) to capture the structural heterogeneity of Autism Spectrum Disorder? Here, we extended the phenotype learning with a hierarchical approach into primary and secondary levels of phenotypes. That approach yields a significantly improved clustering resulting into 2 main ASD phenotypes (there might be more, but we do not have sufficient samples). We also gave the overall method finally a name (PRADA for Phenotype Representation and Analysis via Discriminative Atypicality). IBIS Annual Meeting 2025 May 29 (~9-5:00) & May 30 (~9-12:00) UMN Minneapolis, MN Our group Hotel is The Graduate Please make your reservations with this link -Or call the hotel at (612) 379-8888, press 2 for reservations, & request the IBIS Autism Research Meeting 2025 room block -Please book a room for the nights of 5/28 and 5/29 (at least). More details to come. Stay tuned! Have a fabulous and restful weekend! Chad -------------- next part -------------- An HTML attachment was scrubbed... URL: From cchappel at med.unc.edu Fri Mar 14 17:52:15 2025 From: cchappel at med.unc.edu (Chappell, Chad) Date: Fri, 14 Mar 2025 21:52:15 +0000 Subject: [Ace-recruitment] IBIS Network - Week In Review - 3/14/2025 In-Reply-To: <8802CB6A-86AD-452C-8156-33EC1A2C8B6C@med.unc.edu> References: <4CE497B8-8CF1-4B8D-BFF1-7434BAE3DEC0@med.unc.edu> <301BB957-BDFD-461A-8BEF-FC6BB90243B3@med.unc.edu> <4429ADBB-E418-4A1D-B9F6-D668A1BF208E@med.unc.edu> <6133D561-4809-4C76-BA60-A7ED0B8082B8@med.unc.edu> <44BE26D7-E8B2-4A4B-8FFB-8714AE18BECC@med.unc.edu> <171A7FF3-1C1C-4D10-9C52-FB829D373268@med.unc.edu> <55E64F6D-EA94-4088-9C4C-5A8866F27375@med.unc.edu> <110A51CD-F2E9-4DA8-8830-881B6DBBAD47@med.unc.edu> <96FA8F52-598D-4B8D-AA8D-877658827C77@med.unc.edu> <9E7B52DB-F791-4278-9388-E19680AC4857@med.unc.edu> <8802CB6A-86AD-452C-8156-33EC1A2C8B6C@med.unc.edu> Message-ID: <77B54F6D-E697-4326-B6A3-3C3E642BBF67@med.unc.edu> IBIS Week In Review 3/14/2025 IBIS Executive Committee Approvals Austin Ferguson, John Pruett, and team 6mo fcMRI-EEG Peak Alpha Frequency/Weighted Mean Frequency Correlates For the 6m age group, we will instead explore two measures chosen as proxies for PAF. Weighted mean frequency (WMF) measures the 'center of mass' of the power distribution as a function of frequency over a particular frequency band. Abby Dickenson has found that the WMF over the alpha band (6-9Hz) highly correlates with PAF (for subjects who have developed PAF), and that WMF over the transition band (4.5-7.5Hz) between theta and alpha strongly differentiates between subjects who have developed PAF and those who haven't. Given that these can be computed for all subjects, they will provide convenient measures for exploration in this age group. Rebecca Grzadzinski Pupillary Reaction to Social Stimuli as a Marker of Atypical Social Arousal in Infants at High Likelihood(HL) for ASD and those with DS. Update to already apporved project As a part of Becca?s K award, imaging data was added to Becca's prior approved work with pupillary data. Jessica Girault Mapping Visual System Microstructure to Visual Processing in Infants Abstract for a BBRF Young Investigator proposal - Atypical visual processing is a feature of multiple neuropsychiatric disorders (NPDs) including early-onset disorders like autism spectrum disorder (ASD), as well as ADHD, schizophrenia and mood disorders that emerge later in development. Visual processing and perceptual abilities develop rapidly during infancy and impact cognition and learning, but their developmental neurobiology remains poorly understood. This BBRF project will apply novel methodological approaches to existing neuroimaging and electroencephalography datasets to examine developmental patterns of neurite density and myelination of visual circuitry in relation to macroscale neuronal firing measured across the occipital cortex in response to visual stimuli. This work is motivated by our recent converging reports of atypical visual system structural and functional development during the first year of life, and beyond, in infants at-risk for ASD. We hypothesize that microstructural changes from 6 to 12 months of age in visual circuitry will be related to individual variability in visually evoked neuronal firing patterns in a sample of more than 100 at-risk infants; one third of whom will go on to develop an NPD. Findings from this project will further our understanding of neural mechanisms that support rapid gains in visual processing across the first year of life and has the potential to inform targets and timing for early interventions centered on a highly plastic sensory system. Future directions for this program of research include longitudinal investigations linking early visual circuit properties to later brain function and neuropsychiatric traits including ASD symptoms, attention problems, and anxiety that will be measured as this cohort is followed into school-age. IBIS Annual Meeting 2025 May 29 (~9-5:00) & May 30 (~9-12:00) UMN Minneapolis, MN Our group Hotel is The Graduate Please make your reservations with this link -Or call the hotel at (612) 379-8888, press 2 for reservations, & request the IBIS Autism Research Meeting 2025 room block -Please book a room for the nights of 5/28 and 5/29 (at least). More details to come. Stay tuned! Have a super weekend! Chad -------------- next part -------------- An HTML attachment was scrubbed... URL: