From cchappel at med.unc.edu  Fri Sep  6 17:44:05 2024
From: cchappel at med.unc.edu (Chappell, Chad)
Date: Fri, 6 Sep 2024 21:44:05 +0000
Subject: [Ace-recruitment] IBIS Network - Week In Review - 9/6/2024
In-Reply-To: <2DEE6CE3-87DE-4860-9DC5-4DB3BBF925E5@med.unc.edu>
References: <930D128C-CAB7-4A5B-89BC-71F8E17C8170@med.unc.edu>
 <BF032545-A971-4421-99F4-D4499AD5F05F@med.unc.edu>
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 <FB0421D7-0329-4944-AAC7-7EA8C53A52F3@med.unc.edu>
 <89422378-5427-4F98-9377-985F71697856@med.unc.edu>
 <8FAB27B0-8368-4A09-891C-F2DE98E9DC80@med.unc.edu>
 <947CE503-BB73-4276-A736-01B252CDBDD0@med.unc.edu>
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 <6A212B92-F28A-4CEE-BD52-10E9B22EFD0E@med.unc.edu>
 <24DE3340-91F2-4963-B6E0-AE742CA93428@med.unc.edu>
 <4D67A4C4-520F-4CA1-9008-97BEFAEE047C@med.unc.edu>
 <808093B6-6E4A-48B7-B41D-71389422F1B7@med.unc.edu>
 <D267CCBD-ECEA-4B96-934E-29B4505FCECF@med.unc.edu>
 <2DEE6CE3-87DE-4860-9DC5-4DB3BBF925E5@med.unc.edu>
Message-ID: <FFC3ADA5-FC11-495E-B6FC-A8BD425B16FB@med.unc.edu>

IBIS Week In Review
9/6/2024


IBIS EP
Data Lock
Sites should continue to work toward the uploading and final cleaning of all data before the planned data lock.
The data lock will occur:  OCTOBER 5, 2024

IBIS Funding News
Congratulations to Tanya for receiving internal UW funding to look at IBIS EF data longitudinally!

IBIS EC Approvals
Natasha and the Sex differences Workgroup - Paper Proposal
Investigating early sex differences in language in infants at increased familial risk of autism spectrum disorders
The work on this paper began with a medical student, Jackie, whom Natasha mentored and who presented our initial results at an INSAR meeting a few years ago.  We found that at 12 months, HL males who went on to have ASD showed relatively lower language compared to HL females who went on to have ASD. Since then, Kevin Donovan and Isa Stallworthy refined analyses and Tyler McFayden has joined the project and is taking the lead on getting this to the finish line.

Jason Stein - Presentation Proposal
Evaluating the fidelity of cortical organoids derived from induced pluripotent stem cells (iPSCs) to early human cerebral cortex development
An undergraduate who joined Jason's lab over the summer as part of the Carolina Summer Fellowship program is interested in presenting some of her work at an undergraduate conference (NeuroNovember).

Meera - Paper Proposal
Canonical babbling (CB), a combination of well-formed consonants and vowels, is one of the earliest speech milestones.  It has been explored as a potential marker for speech-language delay in neurodevelopmental disorders, but the findings are mixed. This study aimed to investigate CB in infants at elevated familial likelihood for ASD (EL-ASD) who later received an ASD diagnosis, compare them to elevated likelihood infants who did not develop ASD (EL-Neg), and typically developing infants (LL-Neg). Data from 68 infants was collected using day-long audio recordings at 9 and 15 months using the Language ENvironment Analysis (LENA) digital language recorders. CB, CB ratios and CB stage (if CBR was <0.15) were measured using naturalistic listening methods combined with hand annotations. Developmental and diagnostic assessments were conducted at 24 or 36 months. The study found that at 9 months, EL-ASD infants were less likely to reach the canonical babbling stage compared to EL-Neg and LL-Neg infants. However, there were no significant differences in mean CBRs at 9 or 15 months among the three groups. Additionally, CBRs at 9 and 15 months were not associated with later language skills or autism severity.

Have a wonderful weekend everyone!

Chad

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From cchappel at med.unc.edu  Fri Sep 13 17:30:56 2024
From: cchappel at med.unc.edu (Chappell, Chad)
Date: Fri, 13 Sep 2024 21:30:56 +0000
Subject: [Ace-recruitment] IBIS Network - Week In Review - 9/13/2024
In-Reply-To: <FFC3ADA5-FC11-495E-B6FC-A8BD425B16FB@med.unc.edu>
References: <930D128C-CAB7-4A5B-89BC-71F8E17C8170@med.unc.edu>
 <BF032545-A971-4421-99F4-D4499AD5F05F@med.unc.edu>
 <A9404318-7D1D-4912-B2DA-16D79D73ECF2@med.unc.edu>
 <CF4898AA-1F44-43B9-B030-5986EE3E60F6@med.unc.edu>
 <99824892-1079-44F9-9453-259A87D10171@med.unc.edu>
 <A3755C2B-B203-4936-8607-19D110B249CE@med.unc.edu>
 <B578D626-C137-49D6-86B2-FD373A1D3E3E@med.unc.edu>
 <06E67645-7A0E-4649-BC96-42D6C627A168@med.unc.edu>
 <FB0421D7-0329-4944-AAC7-7EA8C53A52F3@med.unc.edu>
 <89422378-5427-4F98-9377-985F71697856@med.unc.edu>
 <8FAB27B0-8368-4A09-891C-F2DE98E9DC80@med.unc.edu>
 <947CE503-BB73-4276-A736-01B252CDBDD0@med.unc.edu>
 <EAF14343-3B80-4FAB-A696-C02140E2397B@med.unc.edu>
 <6A212B92-F28A-4CEE-BD52-10E9B22EFD0E@med.unc.edu>
 <24DE3340-91F2-4963-B6E0-AE742CA93428@med.unc.edu>
 <4D67A4C4-520F-4CA1-9008-97BEFAEE047C@med.unc.edu>
 <808093B6-6E4A-48B7-B41D-71389422F1B7@med.unc.edu>
 <D267CCBD-ECEA-4B96-934E-29B4505FCECF@med.unc.edu>
 <2DEE6CE3-87DE-4860-9DC5-4DB3BBF925E5@med.unc.edu>
 <FFC3ADA5-FC11-495E-B6FC-A8BD425B16FB@med.unc.edu>
Message-ID: <B4E3575E-1F16-4875-8F97-3CDEA764B631@med.unc.edu>

IBIS Week In Review
9/13/2024


IBIS Funding News
HOT OFF THE PRESS:  The IBIS DS INCLUDE U01 submission WILL be funded!
Congratulations to Natasha, Heather, and the rest of the team!

Awards Given to IBIS Members
Mark Shen has been awarded the UNC Hettleman Prize<https://www.unc.edu/posts/2024/09/10/hettleman-prizes-go-to-5-early-career-faculty/> that recognizes faculty members who exemplify innovative research and future career promise.
Congratulations Mark!!!!!

Margaret Reynolds has been selected as the recipient of the 2025 Gunter von Noorden Young Investigator<https://www.aapos.org/meetings/young-investigator> Award.  This award is designed to recognize promising young investigators within the scientific and medical community.
Congratulations Margaret!!!!!

IBIS EP
Data Lock
Sites should continue to work toward the uploading and final cleaning of all data before the planned data lock.
The data lock will occur:  OCTOBER 5, 2024

Have a great weekend everyone!

Chad

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From cchappel at med.unc.edu  Fri Sep 20 17:41:58 2024
From: cchappel at med.unc.edu (Chappell, Chad)
Date: Fri, 20 Sep 2024 21:41:58 +0000
Subject: [Ace-recruitment] IBIS Network - Week In Review - 9/20/2024
In-Reply-To: <B4E3575E-1F16-4875-8F97-3CDEA764B631@med.unc.edu>
References: <930D128C-CAB7-4A5B-89BC-71F8E17C8170@med.unc.edu>
 <BF032545-A971-4421-99F4-D4499AD5F05F@med.unc.edu>
 <A9404318-7D1D-4912-B2DA-16D79D73ECF2@med.unc.edu>
 <CF4898AA-1F44-43B9-B030-5986EE3E60F6@med.unc.edu>
 <99824892-1079-44F9-9453-259A87D10171@med.unc.edu>
 <A3755C2B-B203-4936-8607-19D110B249CE@med.unc.edu>
 <B578D626-C137-49D6-86B2-FD373A1D3E3E@med.unc.edu>
 <06E67645-7A0E-4649-BC96-42D6C627A168@med.unc.edu>
 <FB0421D7-0329-4944-AAC7-7EA8C53A52F3@med.unc.edu>
 <89422378-5427-4F98-9377-985F71697856@med.unc.edu>
 <8FAB27B0-8368-4A09-891C-F2DE98E9DC80@med.unc.edu>
 <947CE503-BB73-4276-A736-01B252CDBDD0@med.unc.edu>
 <EAF14343-3B80-4FAB-A696-C02140E2397B@med.unc.edu>
 <6A212B92-F28A-4CEE-BD52-10E9B22EFD0E@med.unc.edu>
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 <808093B6-6E4A-48B7-B41D-71389422F1B7@med.unc.edu>
 <D267CCBD-ECEA-4B96-934E-29B4505FCECF@med.unc.edu>
 <2DEE6CE3-87DE-4860-9DC5-4DB3BBF925E5@med.unc.edu>
 <FFC3ADA5-FC11-495E-B6FC-A8BD425B16FB@med.unc.edu>
 <B4E3575E-1F16-4875-8F97-3CDEA764B631@med.unc.edu>
Message-ID: <10B55665-9276-48F2-BE11-AB00DA0D10A5@med.unc.edu>

IBIS Week In Review
9/20/2024

IBIS Annual Meeting
Sadly, our 2024 IBIS Annual Meeting planned for NYC has been cancelled.
We will have a virtual meeting over the same dates as previously planned for the in-person meeting (11/14-15)
Details to come.
We are very likely to attach this meeting to INSAR in Seattle, Spring 2025.
Stay tuned.

IBIS EP
Data Lock
Sites should continue to work toward the uploading and final cleaning of all data before the planned data lock.
The data lock will occur:  OCTOBER 5, 2024
Arousal Data
All sites should upload any and all Arousal Task data collected as soon as possible.

IBIS Internship
Recruitment for next summer's IBIS summer internship is ramping up.
Reach out to Kate if you want to talk about a potential intern-mentor match.

IBIS Members
A really nice press release<https://research.unc.edu/2024/09/03/2024-hettleman-prizes-awarded-to-five-exceptional-early-career-faculty/> came out about Mark?s recent UNC Hettleman Prize award.
Congratulations again, Mark!!!!!


Have a fabulous weekend everyone!

Chad


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From cchappel at med.unc.edu  Fri Sep 27 17:51:42 2024
From: cchappel at med.unc.edu (Chappell, Chad)
Date: Fri, 27 Sep 2024 21:51:42 +0000
Subject: [Ace-recruitment] IBIS Network - Week In Review - 9/27/2024
In-Reply-To: <10B55665-9276-48F2-BE11-AB00DA0D10A5@med.unc.edu>
References: <930D128C-CAB7-4A5B-89BC-71F8E17C8170@med.unc.edu>
 <BF032545-A971-4421-99F4-D4499AD5F05F@med.unc.edu>
 <A9404318-7D1D-4912-B2DA-16D79D73ECF2@med.unc.edu>
 <CF4898AA-1F44-43B9-B030-5986EE3E60F6@med.unc.edu>
 <99824892-1079-44F9-9453-259A87D10171@med.unc.edu>
 <A3755C2B-B203-4936-8607-19D110B249CE@med.unc.edu>
 <B578D626-C137-49D6-86B2-FD373A1D3E3E@med.unc.edu>
 <06E67645-7A0E-4649-BC96-42D6C627A168@med.unc.edu>
 <FB0421D7-0329-4944-AAC7-7EA8C53A52F3@med.unc.edu>
 <89422378-5427-4F98-9377-985F71697856@med.unc.edu>
 <8FAB27B0-8368-4A09-891C-F2DE98E9DC80@med.unc.edu>
 <947CE503-BB73-4276-A736-01B252CDBDD0@med.unc.edu>
 <EAF14343-3B80-4FAB-A696-C02140E2397B@med.unc.edu>
 <6A212B92-F28A-4CEE-BD52-10E9B22EFD0E@med.unc.edu>
 <24DE3340-91F2-4963-B6E0-AE742CA93428@med.unc.edu>
 <4D67A4C4-520F-4CA1-9008-97BEFAEE047C@med.unc.edu>
 <808093B6-6E4A-48B7-B41D-71389422F1B7@med.unc.edu>
 <D267CCBD-ECEA-4B96-934E-29B4505FCECF@med.unc.edu>
 <2DEE6CE3-87DE-4860-9DC5-4DB3BBF925E5@med.unc.edu>
 <FFC3ADA5-FC11-495E-B6FC-A8BD425B16FB@med.unc.edu>
 <B4E3575E-1F16-4875-8F97-3CDEA764B631@med.unc.edu>
 <10B55665-9276-48F2-BE11-AB00DA0D10A5@med.unc.edu>
Message-ID: <3D085B28-577D-45D6-9A32-4F99C057963B@med.unc.edu>

IBIS Week In Review
9/27/2024

IBIS Annual Meeting
We were unable to find a suitable plan to attach our 2025 in-person IBIS meeting to INSAR.
We would like to plan a standalone in-person meeting for spring 2025.
Please complete this link to let us know the dates that you would be available for such a meeting (location TBD):
https://forms.office.com/r/n4qW3Fy3UR

IBIS EP
New EP Scanner Series
This change is to address the artifact Martin shared that happens in the AP acquisitions. We are now prioritizing the PA (APinv) acquisition.
Before:
APinv_B0
AP_dir(101/105)
APinv_dir(101/105)

New:
AP_B0
APinv_dir(101/105)
AP_dir(101/105)

Data Lock
Sites should continue to work toward the uploading and final cleaning of all data before the planned data lock.
New priority Bx measures have been identified for this lock:
DSM-5 CBE checklists
DSM-IV-TR CBE checklists
Bayley scores
Vineland scores
The data lock will occur:  OCTOBER 5, 2024
There will likely be another data lock in the future, once more v24 subject are seen.
Please reference the 'ace-behavioral' email thread for more information (subject: IBIS-EP behavior measures for 1st data lock)

IBIS Internship
Recruitment for next summer's IBIS summer internship is ramping up.
Reach out to Kate if you want to talk about a potential intern-mentor match.

IBIS Executive Committee Approvals
Martin Styner
Project - School age DTI analysis
A project proposal to run a first larger analysis for the school age DTI fiber profiles to look at HL-ASD vs HL-Neg, and investigate longitudinal changes as compared to 24 months of age.

Jed Elison
Project - Fixation Density
A proposal to work up the DS eye tracking data in comparison to data collected as part of the Baby Connectome Project.

Presentation - SRCD: Developmental Trajectories of Gaze Toward Dynamic Social Stimuli Differ in Infants with Down Syndrome
Incorporates preliminary findings from the DS eye tracking data.

Have a w?nderbar weekend everyone!

Chad



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