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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Aptos",sans-serif">Hello everyone,</span><span style="font-size:11.0pt;font-family:"Aptos",sans-serif"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Aptos",sans-serif">Dr. Yendiki is a world-renowned expert in methods of acquisition and analysis of diffusion MRI data.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Aptos",sans-serif">Please see the seminar announcement below.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Aptos",sans-serif">There is still an afternoon time slot to meet with her. Please let me know.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Aptos",sans-serif">Regards,<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Aptos",sans-serif">Amir.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Aptos",sans-serif"><o:p> </o:p></span></p>
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<p class="xmsonormal"><i><span style="font-family:"Arial",sans-serif">Please see further below for English version<o:p></o:p></span></i></p>
<p style="line-height:15.0pt"><strong><span style="font-size:14.0pt;font-family:"Arial",sans-serif;color:black">Killam Seminar Series:</span></strong><strong><span style="font-size:14.0pt;font-family:"Arial",sans-serif"> New Frontiers in Imaging the Human Connectome</span></strong><strong><span style="font-size:14.0pt;font-family:"Aptos",sans-serif"><o:p></o:p></span></strong></p>
<p style="line-height:15.0pt"><b><span style="font-size:10.0pt;font-family:"Arial",sans-serif">Anastasia Yendiki</span></b><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:black"><br>
</span><span style="font-size:10.0pt;font-family:"Arial",sans-serif">Professeure associée en radiologie, Harvard Medical School et Massachusetts General Hospital</span><span style="font-size:10.0pt;font-family:"Times New Roman",serif"><o:p></o:p></span></p>
<p style="line-height:15.0pt"><b><span style="font-size:10.0pt;font-family:"Arial",sans-serif">Hôte:</span></b><span style="font-size:10.0pt;font-family:"Arial",sans-serif"> Amir Shmuel<o:p></o:p></span></p>
<p class="xxxmsonospacing"><strong><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Mardi 25 mars 2025</span></strong><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><br>
<strong><span style="font-family:"Arial",sans-serif">16 h 00 HNE</span></strong><br>
<b>Centre de Communications de Grandpré, Le Neuro</b></span><o:p></o:p></p>
<p class="xxxmsonospacing"><span class="xmsohyperlink"><span style="text-decoration:none"> </span></span><o:p></o:p></p>
<p class="xxxmsonospacing"><a href="https://www.eventbrite.com/e/killam-seminar-series-new-frontiers-in-imaging-the-human-connectome-tickets-1290176054309?aff=oddtdtcreator"><b><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:windowtext;text-decoration:none"><img border="0" width="144" height="60" style="width:1.5in;height:.625in" id="x__x005f_x0000_i1037" src="cid:image003.png@01DB9CE2.ED24B770"></span></b></a><o:p></o:p></p>
<p class="xmsonospacing"><i><span style="font-size:12.0pt;font-family:"Arial",sans-serif"> </span></i><o:p></o:p></p>
<p class="xmsonospacing"><i><span style="font-size:12.0pt;font-family:"Arial",sans-serif">*La présentation sera en anglais</span></i><o:p></o:p></p>
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<p style="line-height:15.0pt"><strong><span style="font-size:14.0pt;font-family:"Arial",sans-serif">Killam Seminar Series: New Frontiers in Imaging the Human Connectome</span></strong><strong><span style="font-size:14.0pt;font-family:"Aptos",sans-serif"><o:p></o:p></span></strong></p>
<p style="line-height:15.0pt"><b><span style="font-size:10.0pt;font-family:"Arial",sans-serif">Anastasia Yendiki</span></b><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:black"><br>
</span><span style="font-size:10.0pt;font-family:"Arial",sans-serif">Associate Professor in Radiology, Harvard Medical School and Massachusetts General Hospital</span><span style="font-size:10.0pt;font-family:"Times New Roman",serif"><o:p></o:p></span></p>
<p style="line-height:15.0pt"><b><span style="font-size:10.0pt;font-family:"Arial",sans-serif">Host:</span></b><span style="font-size:10.0pt;font-family:"Arial",sans-serif"> Amir Shmuel</span><strong><span style="font-family:"Aptos",sans-serif;font-weight:normal"><o:p></o:p></span></strong></p>
<p style="line-height:15.0pt"><strong><span style="font-size:10.0pt;font-family:"Arial",sans-serif">Tuesday, March 25, 2025</span></strong><b><span style="font-size:10.0pt;font-family:"Arial",sans-serif"><br>
<strong><span style="font-family:"Arial",sans-serif">4 p.m. EST</span></strong></span></b><span style="font-size:10.0pt;font-family:"Arial",sans-serif"><br>
<b>De Grandpré Communications Centre, The Neuro</b></span><span style="font-family:"Times New Roman",serif"><o:p></o:p></span></p>
<p style="line-height:15.0pt"><a href="https://www.eventbrite.com/e/killam-seminar-series-new-frontiers-in-imaging-the-human-connectome-tickets-1290176054309?aff=oddtdtcreator"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:windowtext;text-decoration:none"><img border="0" width="144" height="60" style="width:1.5in;height:.625in" id="Picture_x0020_13" src="cid:image004.png@01DB9CE2.ED24B770"></span></a><span style="font-size:10.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></p>
<p style="text-align:justify;line-height:15.0pt"><b><span style="font-size:10.0pt;font-family:"Arial",sans-serif">Abstract:</span></b><span style="font-size:10.0pt;font-family:"Arial",sans-serif"> To this day, critical procedures in neurosurgery and neuromodulation
for patients with devastating diseases are guided by knowledge on how the brain is wired that derives largely from animal studies. Such studies rely on the precision of techniques, like tracer injections, that are not feasible in human subjects. Inter-species
homologies, particularly between non-human primates and humans, are then used to extrapolate information from the former to the latter. This approach has afforded us an understanding of broad organizational principles in the wiring of the human brain, but
crucial details are missing. Recent advances in ex vivo tissue processing and microscopy show great promise for imaging the wiring of the human brain down to the scale of single axonal projections. Much work is needed, however, to turn these breakthroughs
into tools in the hands of anatomists. Doing so will allow us to map precisely, for the first time, clinically relevant brain circuits and to design better therapeutic interventions. It will also provide the ground truth that we need to harness recent advances
in artificial intelligence and improve noninvasive imaging of the wiring of the brain with diffusion MRI. In this talk, Anastasia will present the center for Large-scale Imaging of Neural Circuits (LINC), a multi-institutional consortium funded by the NIH
BRAIN Initiative to lay the technological groundwork for imaging the wiring of the human brain across scales, from the large highways to the small fascicles and down to the single axon level. Anastasia will discuss the image acquisition and analysis advances
that will be needed to make this previously unattainable goal a reality.</span><strong><span style="font-family:"Aptos",sans-serif;font-weight:normal"><o:p></o:p></span></strong></p>
<p style="text-align:justify;line-height:15.0pt"><strong><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:black">The Killam Seminar Series at The Neuro</span></strong><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:black"><br>
Supported by the generosity of the Killam Trusts, The Neuro’s Killam Seminar series hosts outstanding guest speakers whose research is of interest to our scientific community.</span><span style="font-family:"Times New Roman",serif"><o:p></o:p></span></p>
<p style="line-height:15.0pt"><strong><span style="font-size:10.0pt;font-family:"Arial",sans-serif">Visit the event</span></strong><span style="font-size:10.0pt;font-family:"Times New Roman",serif"><a href="https://www.mcgill.ca/neuro/channels/event/killam-seminar-series-new-frontiers-imaging-human-connectome-364263"><span style="font-family:"Arial",sans-serif">
web page</span></a></span><strong><span style="font-size:10.0pt;font-family:"Arial",sans-serif;font-weight:normal">
</span></strong><strong><span style="font-size:10.0pt;font-family:"Arial",sans-serif">for more information.</span></strong><span style="font-size:10.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></p>
<p class="MsoNormal"><strong><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:black">Contact:
</span></strong><a href="mailto:debbie.rashcovsky@mcgill.ca"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:windowtext">Debbie Rashcovsky</span></a><span style="font-family:"Arial",sans-serif"><o:p></o:p></span></p>
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