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<div dir="auto"><span style="font-family:Helvetica">Hi BIC, happening at 4 today @DGP. </span><br>
<span style="font-family:Helvetica">Cheers, </span><br>
<span style="font-family:Helvetica">Boris </span></div>
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<div name="messageReplySection">---------- Forwarded message ----------<br>
<b>Date:</b> Nov 14, 2022, 1:48 AM -0500<br>
<b>To:</b> NeuroEvents <events.neuro@mcgill.ca><br>
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<p class="xmsonormal"><b><span style="font-size:14.0pt;font-family:"Arial",sans-serif;color:black;letter-spacing:.4pt;background:white">Linking microscopy-derived microstructure to MRI signals throughout the macaque brain</span></b></p>
<p class="xmsonormal"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif"> </span></b></p>
<p class="xmsonormal"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Amy Howard</span></b></p>
<p class="xmsonormal"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Postdoctoral researcher, Diffusion MRI, University of Oxford, UK</span></p>
<p class="xmsonormal"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"> </span></p>
<p class="xmsonormal"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Wednesday, November 16, 2022</span></b></p>
<p class="xmsonormal"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">4 p.m. EST</span></b></p>
<p class="xmsonormal"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">The Neuro, 3801 rue University, De Grandpr<span style="color:black;background:white">é</span> Communications Centre</span></b></p>
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<p class="xmsonormal"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.eventbrite.ca%2Fe%2Ffeindel-brain-and-mind-seminar-amy-howard-tickets-453053734917&data=05%7C01%7Cboris.bernhardt%40mcgill.ca%7Cb6a0b145b998493c388408dac670df9a%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638040485353858566%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=3zv3yZwPwiAixN%2FPRl6YnZvVDwQLt7h9jmSU0Cy6tx8%3D&reserved=0" originalsrc="https://www.eventbrite.ca/e/feindel-brain-and-mind-seminar-amy-howard-tickets-453053734917" shash="ZrKuBpczBWFJuPSjEk9cHRZ0RqWXIbf3+RV4FUl5fB/q2GzfufVBlLfHjlqgGItyadX9YRYOnEH7C+qIKjd9YHgruiObdo0sa+TLEBGKcyBBHxSoq4H+wtycsZpwYT6EpyXPyxxUNEjpc6MaCV8MoRE1LUM/skvKVAxomiORO6A="><span style="color:#0563C1">You
must register</span><span style="color:#0563C1;font-weight:normal"> </span><span style="color:#0563C1">here to attend in person</span></a></span></b>
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<p class="xmsonormal" style="text-align:justify;text-justify:inter-ideograph"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Abstract</span></b><span style="font-size:11.0pt">:</span>
<span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:black;background:white">
Understanding brain structure and function often requires combining data across different modalities and scales to link microscale cellular structures to macroscale features of whole brain organisation. Here we introduce the BigMac dataset, a resource combining
in vivo MRI, extensive postmortem MRI and multi-contrast microscopy for multimodal characterisation of a single whole macaque brain. The data spans modalities (MRI and microscopy), tissue states (in vivo and postmortem), and four orders of spatial magnitude,
from microscopy images with micrometre or sub-micrometre resolution, to MRI signals on the order of millimetres. Crucially, the MRI and microscopy images are carefully co-registered together to facilitate quantitative multimodal analyses. In this talk I will
detail the acquisition, curation, and first release of the data, that together make BigMac a unique, openly-disseminated resource available to researchers worldwide. Further, I will demonstrate example analyses and opportunities afforded by the data, including
improvement of connectivity estimates from ultra-high angular resolution diffusion MRI, neuroanatomical insight provided by polarised light imaging and myelin-stained histology, and the joint analysis of MRI and microscopy data for reconstruction of the microscopy-inspired
connectome.</span></p>
<p class="xmsonormal" style="text-align:justify;text-justify:inter-ideograph"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:black;background:white"> </span><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif"> </span></b></p>
<p class="xmsonormal"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">The Feindel Seminar Series at The Neuro</span></b></p>
<p class="xmsonormal"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Advances the vision of Dr. William Feindel (1918–2014), Former Director of the Neuro (1972–1984), to constantly bridge the clinical and research realms. The talks will highlight
the latest advances and discoveries in neuropsychology, cognitive neuroscience, and neuroimaging.</span></p>
<p class="xmsonormal"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"> </span></p>
<p class="xmsonormal"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Speakers will include scientists from across The Neuro, as well as colleagues and collaborators locally and from around the world. The series is intended to provide a virtual
forum for scientists and trainees to continue to foster interdisciplinary exchanges on the mechanisms, diagnosis and treatment of brain and cognitive disorders.</span></p>
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<h1 style="margin:0in"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;font-weight:normal"> </span></h1>
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<b><span style="font-size:12.0pt;line-height:115%;font-family:"Arial",sans-serif;color:black">Contact:</span></b><span style="font-size:12.0pt;line-height:115%;font-family:"Arial",sans-serif;color:black"> </span><span style="font-size:11.0pt;line-height:115%"><a href="mailto:sasha.kelly@mcgill.ca"><span style="font-size:12.0pt;line-height:115%;font-family:"Arial",sans-serif;color:#0563C1">Sasha
Kelly</span></a></span><span style="font-size:12.0pt;line-height:115%;font-family:"Arial",sans-serif">, Conference and Events Coordinator, The Neuro</span></p>
<p style="margin-bottom:7.5pt;line-height:15.0pt"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><img border="0" width="960" height="187" style="width:10.0in;height:1.9479in" id="x_Picture_x0020_4" src="cid:image009.png@01D8CCE0.E8E6CC90"></span></p>
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<p align="center" style="text-align:center;line-height:15.0pt"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"> </span></p>
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