<html>
<head>
<meta http-equiv="Content-Type" content="text/html; charset=utf-8">
<style type="text/css" style="display:none;"> P {margin-top:0;margin-bottom:0;} </style>
</head>
<body dir="ltr">
<div style="font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);" class="elementToProof">
<b>Open for registration</b> (NEUR602-006 in the Fall2022): <span style="color: rgb(0, 0, 0); font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt;">Neuroinformatics for Advancing Precision Medicine in Neurology</span></div>
<div style="font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);" class="elementToProof">
<div>Instructor: Yasser Iturria-Medina, PhD.</div>
<div>Invited Presenters/Assistants: Nikhil Bhagwat, <span style="color: rgb(0, 0, 0); font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 16px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400;">Sue-Jing
Lin,</span><span style="color: rgb(0, 0, 0); font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 16px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400;"> </span>Quadri Adewale, Ahmed F. Khan, Lazaro
Rodriguez Sanchez, Robert Tobias Baumeister.</div>
<div>Location: MNI, Penfield Pavilion, room 282. Virtual if lock-down.</div>
<div>Time (to be modified if needed by students): Flexible</div>
<div><b>Description</b>:</div>
<div>Progressive diseases (e.g., neurodegenerative conditions) start with non-detectable clinical symptoms and may take years (or even decades) to develop. Predicting the distinctive individual course of a progressive disorder, and understanding its underlaying
causes, is of crucial importance for accurate diagnosis and personalized therapeutic intervention. However, in practice, there are multiple challenges associated to this problem, such as a high inter-subject variability within the same disorder and the lack
of robust disease biomarkers. A growing number of studies have attempted to overcome this gap by using Big-Data and sophisticated statistical and computational models, including novel Artificial Intelligence techniques. This course will focus on state-of-the-art
neuroinformatic models (using multi-omics molecular, multi-modal brain imaging, wearable devices and/or clinical data) characterizing disease evolution and heterogeneity, with the ultimate goal of accelerating
<b>Precision Medicine</b><span style="background-color:rgb(255, 255, 255);display:inline !important"><span> </span>in neurology</span>.</div>
<div><b>Objectives of the section</b>:</div>
<div>- To familiarize the student with the main concepts and requirements of disease progression/heterogeneity tools oriented towards Precision Medicine (PM).</div>
<div>- To understand the principles of state-of-art neuroinformatic models/tools based on multi-omics (e.g., [epi]genome, transcriptome), multi-modal brain imaging (e.g., PET, fMRI, DTI, MRI), medical records, wearable devices, and cognitive/clinical data.</div>
<div>- Design experiments and apply some of these models to real data.</div>
<div><br>
</div>
<div><span class="gmail_default" style="font-family:Arial, Helvetica, sans-serif;font-size:small"></span><span style="color:rgb(34, 34, 34);font-family:Arial, Helvetica, sans-serif;font-size:small;background-color:rgb(255, 255, 255);display:inline !important">-----</span><br style="color:rgb(34, 34, 34);font-family:Arial, Helvetica, sans-serif;font-size:small">
</div>
<div>
<div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature" style="color:rgb(34, 34, 34);font-family:Arial, Helvetica, sans-serif;font-size:small">
<div dir="ltr">
<div dir="ltr">
<div dir="ltr">
<div dir="ltr">
<div dir="ltr">
<div dir="ltr">
<div dir="ltr">
<div dir="ltr">
<div dir="ltr">Yasser Iturria Medina, PhD.</div>
<div dir="ltr">Canada Research Chair in Multimodal Data Integration in Neurodegeneration<br>
</div>
<div dir="ltr">Neuroinformatics for Personalized Medicine lab (<a href="http://www.neuropm-lab.com/" target="_blank" style="color:rgb(17, 85, 204)">http://www.neuropm-lab.com/</a>)</div>
<div>Montreal Neurological Institute, McGill University<br>
</div>
<div dir="ltr"><span style="color: rgb(34, 34, 34); font-family: Arial, Helvetica, sans-serif; font-size: small;">Check our last articles: </span><br>
</div>
</div>
</div>
</div>
</div>
</div>
</div>
</div>
</div>
</div>
<div style="margin:0px;font-size:small;font-family:Arial, Helvetica, sans-serif;color:rgb(34, 34, 34);background-color:rgb(255, 255, 255)">
<a href="https://doi.org/10.1038/s41531-022-00332-9" target="_blank" style="margin:0px;color:rgb(17, 85, 204)">https://doi.org/10.1038/s41531-022-00332-9</a><br>
</div>
<div style="margin:0px;font-size:small;font-family:Arial, Helvetica, sans-serif;color:rgb(34, 34, 34);background-color:rgb(255, 255, 255)">
<a href="https://doi.org/10.1093/brain/awab375" target="_blank" style="margin:0px;color:rgb(17, 85, 204)">https://doi.org/10.1093/brain/awab375</a><br>
</div>
<div style="margin:0px;font-size:small;font-family:Arial, Helvetica, sans-serif;color:rgb(34, 34, 34);background-color:rgb(255, 255, 255)">
<a href="https://doi.org/10.1038/s41598-022-09506-0" target="_blank" style="margin:0px;color:rgb(17, 85, 204)">https://doi.org/10.1038/s41598-022-09506-0</a><br>
</div>
<span style="margin:0px;font-size:small;font-family:Arial, Helvetica, sans-serif;color:rgb(34, 34, 34);background-color:rgb(255, 255, 255)"><a href="https://doi.org/10.1038/s42003-021-02133-x" target="_blank" style="margin:0px;color:rgb(17, 85, 204)">https://doi.org/10.1038/s42003-021-02133-x</a></span><br>
</div>
<div><br>
</div>
</div>
</body>
</html>