<html xmlns="http://www.w3.org/1999/xhtml">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=utf-8">
<title></title>
</head>
<body>
<div name="messageBodySection">
<div dir="auto">Hi BIC and FYI - <br>
Special epilepsy centre lecture on connectome & cognition studies in the epilepsies by Prof Carrie McDonald this Thursday at 4PM <br>
(on zoom, see below)<br>
Boris </div>
</div>
<div name="messageReplySection">---------- Forwarded message ----------<br>
<b>From:</b> Deborah Rashcovsky <debbie.rashcovsky@MCGILL.CA><br>
<b>Date:</b> Apr 5, 2022, 2:31 PM -0400<br>
<b>To:</b> MNISTAFF@LISTS.MCGILL.CA <MNISTAFF@LISTS.MCGILL.CA><br>
<b>Subject:</b> NEURO Epilepsy Lecture Series - Imaging Brain Networks in Epilepsy: Determining the Neural Basis of Cognitive and Clinical Co-Morbidities - April 21, 2022<br>
<br>
<blockquote type="cite" style="border-left-color: grey; border-left-width: thin; border-left-style: solid; margin: 5px 5px;padding-left: 10px;">
<div class="WordSection1">
<div align="center">
<table class="MsoNormalTable" border="0" cellspacing="3" cellpadding="0" width="1074" style="width:805.4pt;mso-cellspacing:2.2pt;mso-yfti-tbllook:1184;mso-padding-alt:0in 0in 0in 0in">
<tbody>
<tr style="mso-yfti-irow:0;mso-yfti-firstrow:yes">
<td width="1068" style="width:801.0pt;background:white;padding:7.5pt 7.5pt 0in 7.5pt">
<table class="MsoNormalTable" border="0" cellspacing="3" cellpadding="0" width="949" style="width:711.75pt;mso-cellspacing:2.2pt;mso-yfti-tbllook:1184;mso-padding-alt:0in 0in 0in 0in">
<tbody>
<tr style="mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes">
<td width="478" valign="bottom" style="width:358.5pt;padding:.75pt .75pt .75pt .75pt">
<div align="center">
<table class="MsoNormalTable" border="0" cellspacing="3" cellpadding="0" width="478" style="width:358.5pt;mso-cellspacing:2.2pt;mso-yfti-tbllook:1184;mso-padding-alt:0in 0in 0in 0in">
<tbody>
<tr style="mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes">
<td valign="top" style="padding:7.5pt 7.5pt 7.5pt 0in">
<table class="MsoNormalTable" border="0" cellspacing="3" cellpadding="0" style="mso-cellspacing:2.2pt;mso-yfti-tbllook:1184;mso-padding-alt:0in 0in 0in 0in">
<tbody>
<tr style="mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes">
<td valign="top" style="padding:.75pt .75pt .75pt .75pt">
<p><a href="https://mcgill.ca/neuro/" target="_blank"><span style="font-size:10.0pt;font-family:"Times New Roman",serif;mso-no-proof:yes;text-decoration:none;text-underline:none"><img border="0" width="468" height="106" id="Picture_x0020_1" src="cid:image001.png@01D848F6.607A92B0" alt="The Neuro's logo"></span></a><span style="font-size:10.0pt;font-family:"Times New Roman",serif"></span></p>
</td>
</tr>
</tbody>
</table>
</td>
</tr>
</tbody>
</table>
</div>
</td>
<td width="471" valign="bottom" style="width:353.25pt;padding:.75pt .75pt .75pt .75pt">
<div align="center">
<table class="MsoNormalTable" border="0" cellspacing="3" cellpadding="0" width="471" style="width:353.25pt;mso-cellspacing:2.2pt;mso-yfti-tbllook:1184;mso-padding-alt:0in 0in 0in 0in">
<tbody>
<tr style="mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes">
<td width="74" valign="bottom" style="width:55.65pt;padding:7.5pt 7.5pt 7.5pt 7.5pt">
</td>
<td valign="bottom" style="padding:3.75pt 3.75pt 15.0pt 3.75pt">
<p><a href="http://twitter.com/TheNeuro_MNI" target="_blank"><span style="font-size:10.0pt;font-family:"Times New Roman",serif;mso-no-proof:yes;text-decoration:none;text-underline:none"><img border="0" width="44" height="44" id="Picture_x0020_2" src="cid:image002.png@01D848F6.607A92B0" alt="Twitter"></span></a><span style="font-size:10.0pt;font-family:"Times New Roman",serif"></span></p>
</td>
<td valign="bottom" style="padding:3.75pt 3.75pt 15.0pt 3.75pt">
<p><a href="https://www.facebook.com/TheNeuroMNI/" target="_blank"><span style="font-size:10.0pt;font-family:"Times New Roman",serif;mso-no-proof:yes;text-decoration:none;text-underline:none"><img border="0" width="44" height="44" id="Picture_x0020_3" src="cid:image003.png@01D848F6.607A92B0" alt="Facebook"></span></a><span style="font-size:10.0pt;font-family:"Times New Roman",serif"></span></p>
</td>
<td valign="bottom" style="padding:3.75pt 3.75pt 15.0pt 3.75pt">
<p><a href="https://www.instagram.com/theneuro_mni/" target="_blank"><span style="font-size:10.0pt;font-family:"Times New Roman",serif;mso-no-proof:yes;text-decoration:none;text-underline:none"><img border="0" width="44" height="44" id="Picture_x0020_4" src="cid:image004.png@01D848F6.607A92B0" alt="Instagram"></span></a><span style="font-size:10.0pt;font-family:"Times New Roman",serif"></span></p>
</td>
<td valign="bottom" style="padding:3.75pt 3.75pt 15.0pt 3.75pt">
<p><a href="https://ca.linkedin.com/company/the-montreal-neurological-institute" target="_blank"><span style="font-size:10.0pt;font-family:"Times New Roman",serif;mso-no-proof:yes;text-decoration:none;text-underline:none"><img border="0" width="44" height="44" id="Picture_x0020_5" src="cid:image005.png@01D848F6.607A92B0" alt="LinkedIn"></span></a><span style="font-size:10.0pt;font-family:"Times New Roman",serif"></span></p>
</td>
<td valign="bottom" style="padding:3.75pt 3.75pt 15.0pt 3.75pt">
<p><a href="https://www.youtube.com/user/MontrealNeuro" target="_blank"><span style="font-size:10.0pt;font-family:"Times New Roman",serif;mso-no-proof:yes;text-decoration:none;text-underline:none"><img border="0" width="44" height="44" id="Picture_x0020_6" src="cid:image006.png@01D848F6.607A92B0" alt="YouTube"></span></a><span style="font-size:10.0pt;font-family:"Times New Roman",serif"></span></p>
</td>
</tr>
</tbody>
</table>
</div>
</td>
</tr>
</tbody>
</table>
</td>
</tr>
<tr style="mso-yfti-irow:1">
<td width="1068" style="width:801.0pt;background:#470A69;padding:.75pt .75pt .75pt .75pt">
<p><span style="font-size:10.0pt;font-family:"Times New Roman",serif;color:white;mso-no-proof:yes"><img border="0" width="936" height="87" id="Picture_x0020_7" src="cid:image007.png@01D848F6.607A92B0" alt="Events Banner"></span><span style="font-size:10.0pt;font-family:"Times New Roman",serif"></span></p>
</td>
</tr>
<tr style="mso-yfti-irow:2;mso-yfti-lastrow:yes">
<td width="1068" style="width:801.0pt;background:white;padding:.75pt .75pt .75pt .75pt">
<p align="center" style="margin:0in;text-align:center"><span style="font-size:10.0pt;font-family:"Times New Roman",serif;color:black;mso-no-proof:yes"><img border="0" width="1066" height="533" id="Picture_x0020_12" src="cid:image008.png@01D848F6.607A92B0" alt="Text Description automatically generated with low confidence"></span><span style="font-size:10.0pt;font-family:"Times New Roman",serif"></span></p>
<p style="margin:0in"><b><span style="font-size:14.0pt;font-family:"Arial",sans-serif;color:black">NEURO Epilepsy Lecture Series -</span></b>
<span style="font-size:14.0pt;font-family:"Arial",sans-serif;color:black"><b>Imaging Brain Networks in Epilepsy:</b>
<b>Determining the Neural Basis of Cognitive and Clinical Co-Morbidities</b></span></p>
<p style="margin:0in"><b> </b></p>
<p style="margin:0in"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:black">Thursday, April 21, 2022</span></b><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif"></span></b></p>
<p style="margin:0in"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:black">4 p.m. EDT</span></b><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif"></span></b></p>
<table class="MsoNormalTable" border="0" cellspacing="3" cellpadding="0" width="969" style="width:726.75pt;mso-cellspacing:2.2pt;mso-yfti-tbllook:1184;mso-padding-alt:0in 0in 0in 0in">
<tbody>
<tr style="mso-yfti-irow:0;mso-yfti-firstrow:yes">
<td style="padding:.75pt .75pt .75pt .75pt">
<h3 style="margin-top:0in"><b><span style="font-family:"Arial",sans-serif;mso-fareast-font-family:"Times New Roman";color:black">Zoom</span></b><span style="font-family:"Arial",sans-serif;mso-fareast-font-family:"Times New Roman";color:black"> </span><span style="font-family:"Arial",sans-serif;mso-fareast-font-family:"Times New Roman"">(<a href="https://www.eventbrite.ca/e/neuro-epilepsy-seminar-series-tickets-289625135577"><b>registration
required</b></a> )</span></h3>
<p class="MsoNormal" style="background:white"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#44546A;letter-spacing:.4pt"> </span></p>
<p class="MsoNormal" style="background:white"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:black;letter-spacing:.4pt">Dr. Carrie McDonald, PhD</span></b></p>
<p class="MsoNormal" style="background:white"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:black;letter-spacing:.4pt">Professor, Radiation Oncology and Psychiatry</span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:black;letter-spacing:.4pt">Neuropsychologist, University of California, San Diego</span></p>
<p class="MsoNormal" style="background:white"><span style="letter-spacing:.4pt"> </span></p>
<p class="MsoNormal" style="text-align:justify;background:white"><b><span style="font-family:"Arial",sans-serif;color:black;letter-spacing:.4pt">Abstract</span></b><span style="font-family:"Arial",sans-serif;color:black;letter-spacing:.4pt">: Over the past
decade, the conceptualization of epilepsy as a network disorder has revolutionized our approach to the study of seizures, as well as psychiatric and cognitive co-morbidities in epilepsy. Brain imaging has been at the forefront of this movement, shifting the
focus from one of identifying epileptic lesions to one defining epileptogenic networks. In parallel, the study of cognitive impairments in epilepsy has shifted from the study of isolated cognitive impairments within epilepsy syndromes (e.g., memory impairments
in temporal lobe epilepsy; TLE) to one that emphasizes cognitive and psychiatric profiles within and across epilepsy syndromes—or cognitive phenotyping. In this talk, Dr. McDonald will describe a 15- year NIH-funded program of research using advanced, quantitative
structural, functional, and diffusion imaging to characterize the neural substrates underlying cognitive co-morbidities in patients with epilepsy. Her talk will highlight network abnormalities associated with cognitive phenotypes in TLE and describe how these
patterns may be useful for identifying patients at risk for progressive cognitive decline. She will also describe network features that predict individualized risk for cognitive decline following epilepsy surgery, as well as possible mechanisms of cognitive
reserve. Finally, Dr. McDonald will review the need to consider how patient-specific risk and resilience factors, including bilingualism, can influence brain and neuropsychological profiles and could modify risk for post-operative cognitive decline. Future
efforts discussed will include the need to harmonize neuropsychological approaches to cognitive phenotyping for deployment in large-scale, international studies. Such global efforts are essential to determine the reproducibility and generalizability of the
current findings, accelerate scientific discoveries, and advance personalized medicine in epilepsy.</span></p>
<p style="text-align:justify"><span style="font-family:"Arial",sans-serif">The Centre of Excellence in Epilepsy at The Neuro (Montreal Neurological Institute-Hospital) is proud to announce the new Epilepsy Lecture Series. The series will include eight lectures
per year covering hot topics in basic and clinical epilepsy research. Topics will be presented by distinguished leaders and rising stars in the field, with the goal of bridging basic and clinical perspectives. We are most pleased to welcome Dr. Carrie McDonald
s our speaker for April.</span></p>
<p style="text-align:justify"><span style="font-family:"Arial",sans-serif">We look forward to seeing you!</span></p>
<p style="margin:0in;text-align:justify"><span style="font-family:"Arial",sans-serif">Boris Bernhardt and Birgit Frauscher</span></p>
<p style="margin:0in;text-align:justify"><span style="font-family:"Arial",sans-serif">Co-Chairs, Epilepsy Lecture Series, The Neuro</span></p>
<p style="text-align:justify"><span style="font-family:"Arial",sans-serif">To register:
<a href="https://www.eventbrite.ca/e/neuro-epilepsy-seminar-series-tickets-289625135577">
eventbrite</a></span></p>
<p style="text-align:justify"><span style="font-family:"Arial",sans-serif">For more information:
<a href="https://www.mcgill.ca/neuro/channels/event/neuro-epilepsy-lecture-series-imaging-brain-networks-epilepsy-determining-neural-basis-cognitive-and-338054">
website</a></span></p>
<p style="text-align:justify"><b><span style="font-family:"Arial",sans-serif;color:black">Contact:</span></b><b><span style="font-family:"Arial",sans-serif"> </span></b><span style="font-family:"Arial",sans-serif"><a href="mailto:Debbie.rashcovsky@mcgill.ca">Debbie
Rashcovsky</a><b>,</b> Events, The Neuro</span></p>
<p style="line-height:15.0pt"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;mso-no-proof:yes"><img border="0" width="1025" height="199" id="Picture_x0020_9" src="cid:image009.png@01D848F6.607A92B0"></span><span style="font-size:10.0pt;font-family:"Arial",sans-serif"></span></p>
</td>
</tr>
<tr style="mso-yfti-irow:1;mso-yfti-lastrow:yes">
<td style="padding:.75pt .75pt .75pt .75pt">
<p align="center" style="text-align:center;line-height:15.0pt"><span style="font-size:10.0pt;font-family:"Times New Roman",serif"> </span></p>
</td>
</tr>
</tbody>
</table>
<p class="MsoNormal"><span style="mso-fareast-font-family:"Times New Roman""></span></p>
</td>
</tr>
</tbody>
</table>
</div>
<p class="MsoNormal"><span lang="EN-CA" style="mso-ansi-language:EN-CA" xml:lang="EN-CA"> </span></p>
<p class="MsoNormal"><span lang="EN-CA" style="mso-ansi-language:EN-CA" xml:lang="EN-CA"> </span></p>
<p class="MsoNormal"><span lang="EN-CA" style="mso-ansi-language:EN-CA" xml:lang="EN-CA"> </span></p>
<p class="MsoNormal"><span lang="EN-CA" style="mso-ansi-language:EN-CA" xml:lang="EN-CA"> </span></p>
</div>
</blockquote>
</div>
</body>
</html>