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<div dir="auto">Hi BIC & FYI: <br>
Armin Raznahan is giving the Killam Lecture on Tuesday at 4PM.<br>
<br>
Best wishes,<br>
Boris</div>
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<b>From:</b> NeuroEvents <events.neuro@MCGILL.CA><br>
<b>Date:</b> Feb 26, 2021, 10:12 AM -0500<br>
<b>To:</b> MNISTAFF@LISTS.MCGILL.CA <MNISTAFF@LISTS.MCGILL.CA><br>
<b>Subject:</b> Neuro Event: March 2, 4 pm - Killam Seminar Series at The Neuro: "Integrative Phenotyping of the Developing Human Brain"<br>
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<p align="center" style="text-align:center;line-height:15.0pt"><span style="font-size:10.0pt;font-family:"Times New Roman",serif"><img border="0" width="963" height="542" style="width:10.0312in;height:5.6458in" id="Picture_x0020_1" src="cid:image008.png@01D70C22.7914D9F0"></span><span style="font-size:10.0pt;font-family:"Times New Roman",serif"></span></p>
<h3><span style="font-family:"Arial",sans-serif">Tuesday<span style="color:black">,</span> March 2, 2021<span style="color:black"> <br>
4:00 - 5:00PM E</span>S<span style="color:black">T<br>
Zoom <a href="https://www.eventbrite.ca/e/killam-seminar-seriesintegrative-phenotyping-of-the-developing-human-brain-tickets-142552360949" target="_blank" title="https://www.eventbrite.ca/e/killam-seminar-series-programmed-axon-death-and-its-roles-in-human-disease-tickets-124102468825">(Registration
Required)</a></span></span></h3>
<h3 style="line-height:15.0pt"><span style="font-family:"Arial",sans-serif;color:black">Livestreaming via <a href="https://vimeo.com/event/266553" target="_blank" title="https://vimeo.com/event/266553">Vimeo</a></span></h3>
<p class="MsoNormal" style="line-height:115%"><b><span style="font-size:13.5pt;line-height:115%;font-family:"Arial",sans-serif;color:black">Speaker: </span></b><b><span style="font-size:13.5pt;line-height:115%;font-family:"Arial",sans-serif"><a href="https://www.nimh.nih.gov/research/research-conducted-at-nimh/research-areas/clinics-and-labs/hgb/sdn/index.shtml">Armin
Raznahan MD, PhD</a></span></b> <b><span style="font-size:13.5pt;line-height:115%;font-family:"Times New Roman",serif"></span></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Chief, Section on Developmental Neurogenomics, Human Genetics Branch, National Institute of Mental Health, Bethesda, USA</span></p>
<p style="text-align:justify;line-height:15.0pt"><strong><span style="font-family:"Arial",sans-serif;color:black">Talk abstract</span></strong><span style="font-family:"Arial",sans-serif;color:black"><br>
</span><span style="font-family:"Arial",sans-serif">The Section on Developmental Neurogenomics (SDN) is dedicated to better understanding the biology of childhood-onset neuropsychiatric disorders in ways that might ultimately help to improve disease prediction,
detection and treatment. We approach this overarching goal by using neuroimaging, genomic and bioinformatic techniques to dissect the architecture of human brain development in health, and in neurogenetic disorders that increase risk for psychiatric symptoms.
This talk will begin with a brief high-level overview of clinical research within the SDN, before drilling down into two recent lines of work that examine: (i) how an understanding of human brain scaling in health can help detect patterns of brain change in
neurogenetic disorders, and (ii) how spatial patterns of brain change in neurogenetic disorders can be “decoded” against reference maps of brain gene expression and histology. Together, these studies seek to repurpose in vivo structural brain MRI scans as
tools for nominating potential genomic mechanisms of disease. A key aspect of this work is reliance on integrative research approaches: between basic and clinical science, and between different spatial scales of biological organization. We hope that such integrative
approaches will help to overcome some of the distinctive challenges that face psychiatric neuroscience, which is trying to resolve biological underpinnings for poorly-defined clinical entities in an unusually complex organ that we have little direct access
to.</span><span style="font-family:"Times New Roman",serif"></span></p>
<p style="text-align:justify;line-height:15.0pt"><b><span style="font-family:"Arial",sans-serif;color:black">To register: </span></b><b><span style="font-family:"Arial",sans-serif"><a href="https://www.eventbrite.ca/e/killam-seminar-seriesintegrative-phenotyping-of-the-developing-human-brain-tickets-142552360949" target="_blank" title="https://www.eventbrite.ca/e/killam-seminar-series-programmed-axon-death-and-its-roles-in-human-disease-tickets-124102468825">Eventbrite<span style="font-weight:normal"> </span></a></span></b><span style="font-family:"Arial",sans-serif;color:black">(with
access to the Q & A function, registration required)</span><span style="font-family:"Times New Roman",serif"></span></p>
<p style="text-align:justify;line-height:15.0pt"><b><span style="font-family:"Arial",sans-serif;color:black">The event will be livestreamed via</span></b><span style="font-family:"Arial",sans-serif;color:black"> <b><a href="https://vimeo.com/event/266553" target="_blank">Vimeo</a></b> (no
access to Q & A function, no registration required)</span><span style="font-family:"Times New Roman",serif"></span></p>
<p class="MsoNormal" style="text-align:justify;line-height:115%"><b><span style="font-family:"Arial",sans-serif;color:black">The Killam Seminar Series at The Neuro</span></b></p>
<p class="MsoNormal" style="text-align:justify;line-height:115%"><span style="font-family:"Arial",sans-serif;color:black">Supported by the generosity of the Killam Trusts, The Neuro’s Killam Seminar series hosts outstanding guest speakers whose research is
of interest to the scientific community at The Neuro and McGill University.</span></p>
<p><b><span style="font-family:"Arial",sans-serif;color:black">Host:</span></b> <span style="font-family:"Arial",sans-serif">
Dr. Boris Bernhardt</span><span style="font-family:"Times New Roman",serif"></span></p>
<p><b><span style="font-family:"Arial",sans-serif;color:black">Contact:</span></b>
<span style="font-family:"Times New Roman",serif"></span><span style="font-family:"Arial",sans-serif"><a href="mailto:sasha.kelly@mcgill.ca">Sasha Kelly</a>, Conference and Events Coordinator, The Neuro</span>
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