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<h3 style="line-height:15pt" class=""><strong class=""><span style="font-family: arial, sans-serif;" class="">Feindel Virtual Brain and Mind Seminar at The Neuro:</span></strong><span style="font-family: arial, sans-serif;" class=""> </span><span style="font-family: arial, sans-serif;" class=""><br class="">
<strong class=""><span style="font-family:'arial' , sans-serif" class="">“Probing the link between spreading brain atrophy and functional connectivity”</span></strong></span></h3>
<h3 style="line-height:15pt" class=""><strong class=""><span style="font-family: arial, sans-serif;" class="">Wednesday, August 12, 2020</span></strong><span style="font-family: arial, sans-serif;" class=""><br class="">
</span><span style="font-size: 12pt; font-family: arial, sans-serif;" class="">4:00 - 5:00PM EST</span><span style="font-family: arial, sans-serif;" class=""><br class="">
<strong class=""><span style="font-family:'arial' , sans-serif" class="">Zoom</span></strong> <a href="https://mcgill.ca/neuro/channels/event/feindel-virtual-brain-and-mind-seminar-neuro-probing-link-between-spreading-brain-atrophy-and-322680" class=""><span style="color:#954f72" class="">(Registration
Required)</span></a></span> <span style="font-family: arial, sans-serif;" class=""><br class="">
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Speaker: <a href="http://jesseab.org/" class=""><span style="color:#954f72" class="">Jesse Brown</span></a> PhD</span></h3><p class=""><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class="">Assistant Professor</span></p><p class=""><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class="">Memory and Aging Center</span></p><p class=""><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class="">Department of Neurology</span></p><p class=""><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class="">University of California San Francisco</span></p><p style="margin-bottom:7.5pt;line-height:15pt" class=""><strong class=""><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class="">Talk abstract</span></strong><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class=""><br class="">
Neurodegenerative diseases appear to progress by spreading through brain networks. I will describe how we determine patient-specific “epicenters” in patients with frontotemporal dementia and use a connectome-based spreading model to forecast future atrophy.
We show that we can accurately predict longitudinal atrophy in most patients and find evidence that degeneration spreads from the epicenter in a nonlinear fashion. This approach raises important questions about the neuroanatomical basis of functional connectivity,
which gradients may shed light on. Building on this, I will share a new study where we derive functional activity gradients, describe a number of novel anatomical and dynamic properties of these gradients, and discuss their implications for selective vulnerability
to disease.</span></p><p style="margin-bottom:7.5pt;line-height:15pt" class=""><strong class=""><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class="">The Feindel Virtual Brain and Mind (VBM) Seminar Series</span></strong><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class=""><br class="">
Advancing the vision of Dr. William Feindel (1918–2014), former Director of the Neuro (1972–1984) and Founding Director of the McConnell Brain Imaging Centre (1984), to constantly bridge the clinical and research realms. The talks will highlight the latest
advances and discoveries in neuropsychology, cognitive neuroscience, and neuroimaging.</span></p><p style="line-height:15pt" class=""><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class="">Speakers will include scientists from across The Neuro, as well as colleagues and collaborators locally and from around the world. The series is intended
to provide a virtual forum for scientists and trainees to continue to foster interdisciplinary exchanges on the mechanisms, diagnosis and treatment of brain and cognitive disorders. If you, or someone you know, would be interested in presenting please contact
us to secure a spot on the schedule.</span></p><p style="margin-bottom:7.5pt;line-height:15pt" class=""><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class="">Looking forward to reconnecting!</span></p><p style="margin-bottom:7.5pt;line-height:15pt" class=""><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class="">Nathan Spreng<br class="">
Boris Bernhardt<br class="">
Bratislav Misic </span></p><p style="margin-bottom:7.5pt;line-height:15pt" class=""><strong class=""><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class="">To register:</span></strong> <span style="font-size:10.5pt;font-family:'arial' , sans-serif" class=""><a href="https://www.eventbrite.ca/e/feindel-virtual-brain-and-mind-seminar-at-the-neuro-presents-jesse-brown-tickets-109003987862" class="">https://www.eventbrite.ca/e/feindel-virtual-brain-and-mind-seminar-at-the-neuro-presents-jesse-brown-tickets-109003987862</a>
</span></p><p style="margin-bottom:7.5pt;line-height:15pt" class=""><strong class=""><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class="">Contact :</span></strong><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class=""> </span><span style="font-size: 10.5pt; font-family: arial, sans-serif;" class="">Sasha
Kelly, Events Coordinator, <a href="mailto:sasha.kelly@mcgill.ca" class="">sasha.kelly@mcgill.ca</a>
</span></p><div style="margin: 0in 0in 0.0001pt; line-height: 15pt;" class=""><img alt="cidimage009.png@01D62DEE.F3B685E0" style="" border="0" class="" apple-inline="yes" id="9BA491DA-C05A-4DEE-A290-8B5851E1531C" src="cid:image008.png@01D66C1E.0D04DED0"></div>
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