From andrea at bic.mni.mcgill.ca Tue Jul 3 11:59:11 2007 From: andrea at bic.mni.mcgill.ca (Andrea Bernasconi) Date: Tue, 03 Jul 2007 11:59:11 -0400 Subject: [BIC-announce] NEUR6002-Bernasconi Message-ID: Hello all, This fall term we are offering a new graduate course entitled "Imaging the healthy and diseased human brain". If you are interested, please contact us for the detailed syllabus. Regards, Neda Bernasconi, MD PhD & Andrea Bernasconi, MD From jennifer.chew at mcgill.ca Thu Jul 5 08:43:26 2007 From: jennifer.chew at mcgill.ca (Jennifer Chew, Ms.) Date: Thu, 5 Jul 2007 08:43:26 -0400 Subject: [BIC-announce] SEMINAR - Models in Computer Assisted Neurosurgery Message-ID: Hi all, Pierre Jannin (Rennes, Fr) is a NEUROMIME collaborator working on image guided surgery. He will be visiting next week and will give a talk on Tuesday (July 10) at 4pm. Please come and see this interesting speaker. -Louis DATE: Tuesday, July 10, 2007 TIME: 4:00 P.M. PLACE: DE Grandpre Communications Centre Models in Computer Assisted NeuroSurgery Pierre Jannin, PhD, INSERM Visages INSERM-INRIA Medical School Universit? de Rennes 1, France Keywords : multimodal image guided neurosurgery, surgical models, surgical ontology Abstract: The objective of this presentation is to demonstrate the needs for models in image guided surgery. We suggest the improvement of information, involved in the surgical process, by translating implicit knowledge into explicit one. Making information explicit goes through the construction of models. In the last 15 years, a lot has been done for building numerical patient specific model from multimodal pre operative images. Image segmentation and registration methods allow defining surgical target(s), some reference areas, areas to be avoided, and trajectories from these images. This model can be displayed in the operating room along with the real patient, thanks to augmented reality and updated by using intra operative images (e.g., 3D US, video images). I will present approaches and systems we developed for multimodal image guided neurosurgery. Image guided surgery made information about the patient more explicit, but lot of information still remains implicit, especially regarding the surgical practice. The high inter patient and inter surgeon variability in neurosurgery has to be studied and modelled for its explicit understanding. I will demonstrate that surgical models are an appropriate solution. I will suggest a global methodology for surgical models including the definition of a surgical ontology, the development of software for surgical experience description based on this ontology, and the analysis of these descriptions for knowledge generation about the surgical practice. This approach will be illustrated in the context of analyzing the relationships between the tumour localization in a lobe and the patient positioning in the OR for a population of 159 surgical cases. Additional examples will outline other facets of surgery which can be addressed. Finally, I will show how this approach can be used in clinical applications. From jennifer.chew at mcgill.ca Mon Jul 9 10:40:49 2007 From: jennifer.chew at mcgill.ca (Jennifer Chew, Ms.) Date: Mon, 9 Jul 2007 10:40:49 -0400 Subject: [BIC-announce] FW: pls forward this talk announcement - Models in Computer Assisted NeuroSurgery Message-ID: Seminar Date: Tuesday, July 10, 2007 Time: 4:00 P.M. Place: de Grandpre Communications Centre Speaker: Pierre Jannin, INSERM, INRIA Title: Models in Computer Assisted NeuroSurgery More details below. Jennifer Chew McConnell Brain Imaging Centre MNI - WB317 3801 University Street Montreal, Qc H3A 2B4 Telephone: 514-398-8554 Fax: 514-398-2975 DETAILS Hi all, Pierre Jannin (Rennes, Fr) is a NEUROMIME collaborator working on image guided surgery. He will be visiting ...and will give a talk on Tuesday (July 10) at 4pm. Please come and see this interesting speaker. -Louis Models in Computer Assisted NeuroSurgery Pierre Jannin, PhD, INSERM Visages INSERM-INRIA Medical School Universit? de Rennes 1, France Keywords : multimodal image guided neurosurgery, surgical models, surgical ontology Abstract: The objective of this presentation is to demonstrate the needs for models in image guided surgery. We suggest the improvement of information, involved in the surgical process, by translating implicit knowledge into explicit one. Making information explicit goes through the construction of models. In the last 15 years, a lot has been done for building numerical patient specific model from multimodal pre operative images. Image segmentation and registration methods allow defining surgical target(s), some reference areas, areas to be avoided, and trajectories from these images. This model can be displayed in the operating room along with the real patient, thanks to augmented reality and updated by using intra operative images (e.g., 3D US, video images). I will present approaches and systems we developed for multimodal image guided neurosurgery. Image guided surgery made information about the patient more explicit, but lot of information still remains implicit, especially regarding the surgical practice. The high inter patient and inter surgeon variability in neurosurgery has to be studied and modelled for its explicit understanding. I will demonstrate that surgical models are an appropriate solution. I will suggest a global methodology for surgical models including the definition of a surgical ontology, the development of software for surgical experience description based on this ontology, and the analysis of these descriptions for knowledge generation about the surgical practice. This approach will be illustrated in the context of analyzing the relationships between the tumour localization in a lobe and the patient positioning in the OR for a population of 159 surgical cases. Additional examples will outline other facets of surgery which can be addressed. Finally, I will show how this approach can be used in clinical applications. From jennifer.chew at mcgill.ca Tue Jul 17 09:50:33 2007 From: jennifer.chew at mcgill.ca (Jennifer Chew, Ms.) Date: Tue, 17 Jul 2007 09:50:33 -0400 Subject: [BIC-announce] FW: MNI Faculty Job Seminar - Tuesday, July 17, 4 pm- AlphaB-crystallin: Protective and Therapeutic in Autoimmune Demyelination Message-ID: PLEASE DISCARD IF THIS IS A DUPLICATE. THANK YOU. JENNIFER ________________________________ From: MNISTAFF - Montreal Neurological Institute Staff [mailto:MNISTAFF at LISTS.MCGILL.CA] On Behalf Of Enza Ferracane, Ms. Sent: Monday, July 16, 2007 8:44 AM To: MNISTAFF at LISTS.MCGILL.CA Subject: MNI Faculty Job Seminar - Tuesday, July 17, 4 pm MNI faculty and students are encouraged to attend a special seminar by a candidate for an MNI faculty position. Speaker: Dr. Shalina Ousman, Post-doctoral fellow Department of Neurology and Neurological Sciences Stanford University Title: AlphaB-crystallin: Protective and Therapeutic in Autoimmune Demyelination Time: 4:00 pm Date: Tuesday, July 17, 2007 Place: de Grandpre Communications Centre Dr. Ousman is a candidate for a faculty position at the MNI. Dr. Ousman's research focuses on the endogenous protective mechanisms in multiple sclerosis. Her research goal is to develop approaches that limit the acute damage to CNS tissue and to prevent secondary damage in chronic MS. She aims to identify endogenous protective molecules and mechanisms in the CNS and immune system; to determine why the relevant molecules or signal transduction pathways are insufficient to curb disease; and to determine how their expression and/or activity could be modulated to limit CNS damage. Dr. Ousman uses MS samples and the EAE animal model to conduct her studies. From jennifer.chew at mcgill.ca Wed Jul 18 14:03:41 2007 From: jennifer.chew at mcgill.ca (Jennifer Chew, Ms.) Date: Wed, 18 Jul 2007 14:03:41 -0400 Subject: [BIC-announce] FW: Dr. Bernd Kaina Presentation - Friday, July 20th - The 06-alkylguanine response Message-ID: PLEASE DISCARD IF THIS IS A DUPLICATE. THANK YOU. JENNIFER ________________________________ From: MNISTAFF - Montreal Neurological Institute Staff [mailto:MNISTAFF at LISTS.MCGILL.CA] On Behalf Of Enza Ferracane, Ms. Sent: Wednesday, July 18, 2007 1:42 PM To: MNISTAFF at LISTS.MCGILL.CA Subject: Dr. Bernd Kaina Presentation - Friday, July 20th Dear all, On Friday July 20th, 2007 Dr. Bernd Kaina Professor of Toxicology, University of Mainz Germany will be at the MNI to give a talk. Dr. Kaina's working area is in cell death (notably in gliomas) induced by alkylating agents. Title of presentation: "The O6-alkylguanine response". Date: Friday July 20, 2007 Time: 2:00PM Place: DeGrandpre Communications Centre/Bell Room Hope to see you all there. Dr. Rolando Del Maestro, MD, PhD, FRCS(C), FACS, DABNS Director, Brain Tumour Research Centre Montreal Neurological Institute and Hospital McGill University 3801 University St., Suite 109 Montreal, Quebec H3A 2B4 From jennifer.chew at mcgill.ca Thu Jul 19 10:20:11 2007 From: jennifer.chew at mcgill.ca (Jennifer Chew, Ms.) Date: Thu, 19 Jul 2007 10:20:11 -0400 Subject: [BIC-announce] FW: EPILEPSY CONFERENCE - July 19, 2007 Message-ID: PLEASE DISCARD IF THIS IS A DUPLICATE. THANK YOU. JENNIFER -----Original Message----- From: MNISTAFF - Montreal Neurological Institute Staff [mailto:MNISTAFF at LISTS.MCGILL.CA] On Behalf Of Enza Ferracane, Ms. Sent: Thursday, July 19, 2007 8:31 AM To: MNISTAFF at LISTS.MCGILL.CA Subject: EPILEPSY CONFERENCE EPILEPSY CONFERENCE - July 19, 2007 Please note exceptional time: 3.30pm. Room 201. There will be a reception in honor of the late Maxime Vilandr?. His parents will attend and express their support for epilepsy research. Refreshments will be served. All are welcome! Seizure Conference will start at 4pm Title: Encephalitis or progressive deterioration ?Seizures From jennifer.chew at mcgill.ca Fri Jul 20 08:58:54 2007 From: jennifer.chew at mcgill.ca (Jennifer Chew, Ms.) Date: Fri, 20 Jul 2007 08:58:54 -0400 Subject: [BIC-announce] FW: Dr. Bernd Kaina Presentation - TODAY "The 06-alkylguanine response" Message-ID: PLEASE DISCARD IF THIS IS A DUPLICATE. THANK YOU. JENNIFER Jennifer ________________________________ From: MNISTAFF - Montreal Neurological Institute Staff [mailto:MNISTAFF at LISTS.MCGILL.CA] On Behalf Of Enza Ferracane, Ms. Sent: Friday, July 20, 2007 8:48 AM To: MNISTAFF at LISTS.MCGILL.CA Subject: Dr. Bernd Kaina Presentation - TODAY Dear all, On Friday July 20th, 2007 Dr. Bernd Kaina Professor of Toxicology, University of Mainz Germany will be at the MNI to give a talk. Dr. Kaina's working area is in cell death (notably in gliomas) induced by alkylating agents. Title of presentation: "The O6-alkylguanine response". Date: Friday July 20, 2007 Time: 2:00PM Place: DeGrandpre Communications Centre/Bell Room Hope to see you all there. Dr. Rolando Del Maestro, MD, PhD, FRCS(C), FACS, DABNS Director, Brain Tumour Research Centre Montreal Neurological Institute and Hospital McGill University 3801 University St., Suite 109 Montreal, Quebec H3A 2B4 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://www.bic.mni.mcgill.ca/pipermail/bic-announce/attachments/20070720/b53e6a0f/attachment.html From jennifer.chew at mcgill.ca Mon Jul 30 11:18:26 2007 From: jennifer.chew at mcgill.ca (Jennifer Chew, Ms.) Date: Mon, 30 Jul 2007 11:18:26 -0400 Subject: [BIC-announce] FW: Dr. Andrew Ioannides lecture on Aug. 1, 2007 from 4:00 p.m. to 5:30 p.m. Magnetoencephalography (MEG): Challenged by and Challenging Neuroscience Message-ID: ***LECTURE*** DATE: Wednesday, August 1, 2007 LOCATION: De Grandpr? Communications Centre - BTRC 3B TIME: 4:00 P.M. to 5:30 P.M. SPEAKER: Dr. Andreas A. Ioannides Lab for Human Brain Dynamics Brain Science Institute (BSI), RIKEN, 2-1 Hirosawa Wako-shi, Saitama 3510198 Japan TITLE: Magnetoencephalography (MEG): Challenged by and Challenging Neuroscience Magnetoencephalography (MEG) has always been associated with excellent temporal resolution. It is now becoming apparent that tomographic analysis of MEG signals can provide accurate localization, at least for places a few centimeters away from the center of the head. It is therefore becoming possible to explore brain function by accurately mapping activity over the entire cortical mantle and probing interactions between areas across timescales ranging from milliseconds to minutes in the same run, for example when a piece of music is played. This capability is however difficult to handle because it is difficult to prove the veracity of the images in the new spatiotemporal domain that the MEG unveils; there is simply no gold standard to compare. This challenge for MEG has been met by two kinds of meaningful tests of accuracy. First, by using other techniques, for example, the responses were analyzed using tomographic analysis of the average data and the results were compared with responses to identical stimuli on the same subjects using fMRI. The loci of activation within V1 for MEG and fMRI agreed to within a few millimeters, which was as good as the coregistration of the data would allow. Alternatively detailed analysis of the spatiotemporal evolution of activity was compared for tasks producing well defined activations thoroughly documented in animal experiments , e.g. for simple visual stimuli, sleep or eye movements. The challenge for MEG now is how to package the information that springs forth from the data analysis into chunks that are meaningful for neuroscience and/or clinically useful. The challenge for Neuroscience is to formulate problems to chart the new spatiotemporal terrain that now becomes accessible from millimeter to many centimeters in space and from millisecond to hours in time. Jennifer (as requested by Dr. Alan Evans) Jennifer Chew McConnell Brain Imaging Centre MNI - WB317 3801 University Street Montreal, Qc H3A 2B4 Telephone: 514-398-8554 Fax: 514-398-2975