[BIC-announce] FW: Killam Speaker Dr. Patrizia Casaccia-Bonnefil - TODAY - Molecular mechanisms of oligodendrocyte progenitor differentiation

[Jennifer Chew, Ms.]

From: MNISTAFF - Montreal Neurological Institute Staff [mailto:MNISTAFF at LISTS.MCGILL.CA] On Behalf Of Enza Ferracane, Ms.
Sent: Tuesday, May 09, 2006 9:01 AM
To: MNISTAFF at LISTS.MCGILL.CA
Subject: Killam Speaker Dr. Patrizia Casaccia-Bonnefil - TODAY
Importance: High
PLEASE DISCARD IF THIS IS A DUPLICATE.  THANK YOU.  JENNIFER 
 
 REMINDER 
 
 
 
KILLAM LECTURE
 Date:  Tuesday, May 9, 2006
 
Speaker:  Patrizia Casaccia-Bonnefil, MD, PhD
Assistant Professor 
Department of Neuroscience and Cell Biology
UMDNJ-Robert Wood Johnson Medical School 
Title:  Molecular mechanisms of oligodendrocyte progenitor differentiation
 
Place:  de Grandpre Communications Centre
 
Time:  4:00 pm 

Research interests:
Strategies for repair in demyelinating conditions, using adult neural stem cells. Identification of novel therapeutic targets for Multiple Sclerosis. Mechanisms of differentiation of lineage restricted oligodendrocyte progenitors. Molecular mechanisms of brain tumors.
Selected Publications 1 
Gokhan, S., Marin-Husstege, M., Yu Yung , S, Fontanez, D., Casaccia-Bonnefil, P. Mehler, M.F. (2005) Coordinate Regulation of Homeodomain and Basic Helix-Loop-Helix Transcription Factors Differentially Regulate Myelin Basic Protein Gene Expression. J. Neurosci., 26:8311-8321. 

Shen, S., Li, J., Casaccia-Bonnefil, P. (2005) Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J. Cell Biol. 169: 577-589. 

Bansal, R., Marin-Husstege,M., Winkler, S., Casaccia-Bonnefil, P. (2005) S-phase entry of oligodendrocyte lineage cells is associated with increased levels of p21Cip1. J. Neurosci. Res., 80:360-8. 

Liu, A, Stadelman C., Mastronardi F., Moscarello M., Sobel A., Casaccia-Bonnefil, P. (2005) Expression of stathmin, a developmentally controlled cytoskeleton regulating molecule, in demyelinating disorders. J. Neurosci. 25:737-47. 

Marin-Husstege, M., Muggironi, M., Raban, D., Skoff, R., Casaccia-Bonnefil, P. (2005) Oligodendrocyte progenitor proliferation and maturation is differentially regulated by male and female sex steroid hormones. Dev. Neurosci. 26:245-54. 

Crockett DP, Burshteyn M, Garcia C, Muggironi M, Casaccia-Bonnefil P. (2005) Number of oligodendrocyte progenitors recruited to the lesioned spinal cord is modulated by the levels of the cell cycle regulatory protein p27Kip-1. Glia. 49:301-8. 

Kim, D., Zhao, X., Tu, C., Casaccia-Bonnefil, P., Chao, M.V. (2004) The neurotrophins prevent apoptotic but not necrotic cell death following neuronal injury by signaling through their TRK receptor. J. Neurosurgery , 100(1):79-87. 

Liu A., M., Muggironi, M., Casaccia-Bonnefil, P. (2003) Oligodendrocyte process outgrowth in vitro is modulated by epigenetic regulation of cytoskeletal severing proteins. Glia,44(3):264-74. 

Petrone A., Dusa, A., Bianchi R., Casaccia-Bonnefil, P., Arancio, O., Sap.J. (2003) Receptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation. EMBO J., 22:4121-4131. 

Marin-Husstege, M., Muggironi, M., Liu A., Casaccia-Bonnefil, P. (2002) Histone deacetylase activity is necessary for oligodendrocyte lineage progression, J. Neurosci., 22: 10333-10345. 

Doetsch, F. Verdugo, J.G., Caille I, Chao MV Alvarez-Buylla Casaccia-Bonnefil, P. (2002) Lack of the cell cycle inhibitor p27Kip1 results in selective increase of transit amplifying cells for adult neurogenesis. J. Neurosci, 22:2256-2264 

Casaccia-Bonnefil, P., Carter, B., Dobrowsky, R.T. and Chao, M.V. (1996) Nerve growth factor mediated cell death of mature oligidendrocytes through the p75 neurotrophin receptor. Nature, 383, 716-719.