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Hi Chad— to be clear— the IRB modification re: twins is applicable to the proband but not the subject in IBIS. Is this right?</div>
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<span style="font-size:11pt;line-height:1.5"><b>Rebecca Grzadzinski, PhD </b></span><span style="font-size:11pt;line-height:1.5">(she/her/hers)</span></p>
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<span style="font-size:11pt;line-height:1.5"></span><span style="font-size:11pt;line-height:1.5">Research Assistant Professor</span></p>
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<span style="font-size:11pt;line-height:1.5"></span><span style="font-size:11pt;line-height:1.5">University of North Carolina (UNC)</span></p>
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<span style="font-size:11pt;line-height:1.5">Carolina Institute for Developmental Disabilities (CIDD)</span></p>
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<div id="divRplyFwdMsg" dir="ltr"><font face="Calibri, sans-serif" style="font-size:11pt" color="#000000"><b>From:</b> ace-behavioral-bounces@bic.mni.mcgill.ca <ace-behavioral-bounces@bic.mni.mcgill.ca> on behalf of Chappell, Chad <cchappel@med.unc.edu><br>
<b>Sent:</b> Friday, April 1, 2022 4:54:52 PM<br>
<b>To:</b> ace-project <ace-project@bic.mni.mcgill.ca>; ace-coordinator@bic.mni.mcgill.ca <ace-coordinator@bic.mni.mcgill.ca>; ace-behavioral@bic.mni.mcgill.ca <ace-behavioral@bic.mni.mcgill.ca>; Ace-mri <ace-mri@bic.mni.mcgill.ca>; Ace-recruitment@bic.mni.mcgill.ca
<Ace-recruitment@bic.mni.mcgill.ca>; ace-acquisition@bic.mni.mcgill.ca <ace-acquisition@bic.mni.mcgill.ca><br>
<b>Subject:</b> [Ace-behavioral] IBIS Network - Week In Review - 4_1_2022</font>
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<div class="" style="word-wrap:break-word; line-break:after-white-space">
<div class="" style="word-wrap:break-word; line-break:after-white-space">IBIS Week In Review <br class="">
4/1/2022 </div>
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<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<div class="" style="word-wrap:break-word; line-break:after-white-space">- IBIS-EP </div>
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<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<div class="" style="word-wrap:break-word; line-break:after-white-space">-IRB Modification Approval</div>
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<div class="" style="word-wrap:break-word; line-break:after-white-space">-updated the TSI to remove twins/multiple births from being exclusionary</div>
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<div class="" style="word-wrap:break-word; line-break:after-white-space">-IBIS-Sleep</div>
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<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<div class="" style="word-wrap:break-word; line-break:after-white-space">-CHOP was IRB approved for data Sleep Project collection</div>
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<div class="">On Mar 25, 2022, at 4:52 PM, Chappell, Chad <<a href="mailto:cchappel@med.unc.edu" class="">cchappel@med.unc.edu</a>> wrote:</div>
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<div class="">
<div class="" style="word-wrap:break-word; line-break:after-white-space">IBIS Week In Review <br class="">
3/25/2022 <br class="">
<br class="">
<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">-IBIS nationwide press release for recent publication:</blockquote>
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<div class="">- Shen (et al.): <u class="">Subcortical Brain Development in Autism and Fragile X Syndrome: Evidence for Dynamic, Age- and Disorder-Specific Trajectories in Infancy</u> in AJP</div>
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<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<div class="">-<a href="https://news.unchealthcare.org/2022/03/scientists-identify-overgrowth-of-key-brain-structure-in-babies-who-later-develop-autism/" class="">UNC Press Release</a></div>
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<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">-IBIS-EC Approval: <br class="">
</blockquote>
<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">- Project Proposal (Burrows) Subgrouping within the VSA data based on clinically-relevant features</blockquote>
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<div class="">On Mar 18, 2022, at 5:09 PM, Chappell, Chad <<a href="mailto:cchappel@med.unc.edu" class="">cchappel@med.unc.edu</a>> wrote:</div>
<br class="x_Apple-interchange-newline">
<div class="">
<div class="" style="word-wrap:break-word; line-break:after-white-space">IBIS Week In Review <br class="">
3/18/2022 <br class="">
<br class="">
<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">-IBIS-EC Approval: <br class="">
</blockquote>
<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">-Unstable Diagnosis Workgroup, headed up by Becca</blockquote>
</blockquote>
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<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">-This new workgroup plans to look at unstable diagnoses in the IBIS dataset to 1) Create a formalized diagnostic impression through a review of all available information on each case,
2.) Generate ideas for a related manuscript, and 3) characterize first-time school-age ASD diagnosed females in our sample (aim associated with sex differences workgroup)</blockquote>
<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">-Please let Becca know if you would like to be added to this workgroup.</blockquote>
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<div class="">On Mar 11, 2022, at 4:32 PM, Chappell, Chad <<a href="mailto:cchappel@med.unc.edu" class="">cchappel@med.unc.edu</a>> wrote:</div>
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<div class="">
<div class="" style="word-wrap:break-word; line-break:after-white-space">
<div class="" style="word-wrap:break-word; line-break:after-white-space">IBIS Week In Review <span class="x_Apple-tab-span" style="white-space:pre">
</span> <span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><br class="">
3/11/2022<span class="x_Apple-tab-span" style="white-space:pre"> </span></div>
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<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<div class="">-IBIS-EP: </div>
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<div class="">-Probands who are twins were confirmed to be non-exclusionary.</div>
<div class="">-New Eye Tracking calibration stimulus was implemented.</div>
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<div class="">- LORIS: A delete button/feature was added to the DQT for saved queries.</div>
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<div class="">-IBIS Executive Committee: </div>
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<div class="">-Proposal Approved: Caravella - cognitive trajectories to define subgroups in the HL sample. </div>
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<div class="">-Will be presented on 3/23 IBIS Analysis Workgroup call.</div>
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<div class="">On Mar 4, 2022, at 5:01 PM, Chappell, Chad <<a href="mailto:cchappel@med.unc.edu" class="">cchappel@med.unc.edu</a>> wrote:</div>
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<div class="">
<div class="" style="word-wrap:break-word; line-break:after-white-space">IBIS Week In Review <span class="x_Apple-tab-span" style="white-space:pre">
</span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><br class="">
3/4/2022<span class="x_Apple-tab-span" style="white-space:pre"> </span><span class="x_Apple-tab-span" style="white-space:pre"></span>
<div class=""><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><br class="">
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<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<div class="">- Sleep Project: </div>
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<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<div class="">-Expanded enrollment age to include down to 4 years old<span class="x_Apple-tab-span" style="white-space:pre">
</span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span></div>
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<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<div class="">-Waived assent of 4 to 6 years old<span class="x_Apple-tab-span" style="white-space:pre">
</span><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span></div>
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<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<div class="">-Updated consent and assent forms to remove signature lines due to waived documentation of signed consent/assent<span class="x_Apple-tab-span" style="white-space:pre">
</span></div>
<div class=""><span class="x_Apple-tab-span" style="white-space:pre"></span><span class="x_Apple-tab-span" style="white-space:pre"></span></div>
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<div class="">-Papers:</div>
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<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
<div class="">-Jessica's paper, "Brain imaging markers of inherited liability for autism implicate infant visual regions and pathways" has been accepted to The American Journal of Psychiatry!!!</div>
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<blockquote class="" style="margin:0 0 0 40px; border:none; padding:0px">
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<div class="">-Archive of IBIS Week In Reviews, through Feb., uploaded to the LORIS Document Repository </div>
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<div class="">-Root > IBIS Administrative Documents</div>
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